丁溴东莨菪碱+坦索罗辛辅助体外冲击波碎石术治疗肾结石的临床效果  

Clinical Effect of Scopolamine Butylbromide+Tamsulosin Assisted Extracorporeal Shock Wave Lithotripsy in Treatment of Kidney Stones

作　　者：廖君屯 温劢 胡聪跃 钟凯华[2] LIAO Juntun;WEN Mai;HU Congyue;ZHONG Kaihua(Second People's Hospital of Wuhua County,Wuhua 514021,China;不详)

机构地区：[1]五华县第二人民医院,广东五华514021 [2]梅州市人民医院

出　　处：《中外医学研究》2020年第33期114-116,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:分析丁溴东莨菪碱+坦索罗辛辅助体外冲击波碎石术治疗肾结石的临床效果。方法:研究对象为笔者所在医院2018年1月-2020年1月纳入的86例肾结石患者,通过双盲选法将其分为参照组和观察组,每组43例。参照组采用丁溴东莨菪碱辅助体外冲击波碎石术治疗,观察组采用丁溴东莨菪碱+坦索罗辛辅助体外冲击波碎石术,比较两组治疗效果、康复情况、炎症水平及不良反应发生情况。结果:观察组治疗总有效率高于参照组,差异有统计学意义(P<0.05);观察组结石排出时间及肾绞痛消失时间均早于参照组,差异均有统计学意义(P<0.05);观察组治疗后IL-6、TNF-α及CRP水平均低于参照组,差异均有统计学意义(P<0.05);观察组不良反应发生率低于参照组,差异有统计学意义(P<0.05)。结论:在肾结石患者的临床治疗中,在行体外冲击波碎石术治疗时,辅以丁溴东莨菪碱+坦索罗辛治疗可以进一步提高临床疗效及治疗安全性,不仅可以有效加快患者病情康复,同时还可以在更大程度上减轻其炎性反应。Objective:To analyze the clinical application of Scopolamine Butylbromide+Tamsulosin assisted extracorporeal shock wave lithotripsy in treatment of kidney stones.Method:The research object was 86 patients with kidney stones treated in our hospital from January 2018 to January 2020,and they were divided into the reference group and the observation group by double-blind selection method,with 43 cases in each group.Patients in the reference group were treated with Scopolamine Butylbromide assisted by extracorporeal shock wave lithotripsy,and patients in the observation group were treated with Scopolamine Butylbromide + Tamsulosin assisted extracorporeal shock wave lithotripsy.Treatment effect,rehabilitation,inflammation level and adverse reactions were compared between the two groups.Result:The total effective rate in the observation group was higher than that in the control group,the difference was statistically significant (P<0.05).The expulsion time of calculi and the disappearance time of renal colic in the observation group were earlier those in the control group,the differences were statistically significant (P<0.05).After treatment,the levels of IL-6,TNF-α and CRP in the observation group were lower than those in the control group,the differences were statistically significant (P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,the difference was statistically significant (P<0.05).Conclusion:In the clinical treatment of patients with renal stones,supplemented with Scopolamine Butylbromide + Tamsulosin during the treatment of extracorporeal shock wave lithotripsy can further improve the clinical efficacy and treatment safety.It can also reduce its inflammatory response to a greater extent.

关 键 词：肾结石 体外冲击波碎石术 丁溴东莨菪碱 坦索罗辛 治疗效果 

分 类 号：R699.2[医药卫生—泌尿科学]