Shizukuishi评分法比较腮腺与颌下腺核素显像对干燥综合征的诊断价值  

Comparison the value of parotid and submandibular gland scintigraphy for the diagnosis of Sjögren's syndrome using Shizukuishi scoring method

作　　者：周明珠[1] 王巍[2] 周航 段婷[1] 宋淑菊[1] Zhou Mingzhu;Wang Wei;Zhou Hang;Duan Ting;Song Shuju(Department of Rheumatology and Immunology,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China;Nuclear Medicine,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)

机构地区：[1]首都医科大学附属北京友谊医院风湿科,100050 [2]首都医科大学附属北京友谊医院核医学科,100050

出　　处：《中华风湿病学杂志》2020年第10期660-663,I0002,共5页Chinese Journal of Rheumatology

基　　金：北京市优秀人才培养资助青年骨干个人项目(2018000021469G196)。

摘　　要：目的应用Shizukuishi评分法比较腮腺与颌下腺核素显像对SS的诊断价值。方法选取SS 124例,对照组91例,分别进行腮腺和颌下腺核素显像检查,以排泄率为标准对每个腺体核素显像结果评分,每个腺体0~3分,应用受试者操作特征曲线(ROC)比较腮腺及颌下腺核素显像对SS的诊断准确性。结果腮腺核素显像评分0~6分,以2分为截断值,诊断SS的敏感度为76.9%,特异度为72.6%,曲线下面积(AUC)为0.798±0.030。颌下腺核素显像评分0~6分,以2分为截断值,诊断SS的敏感度为78.0%,特异度为78.2%,AUC为0.854±0.026。结论颌下腺核素显像对SS的诊断价值更优。Objective Shizukuishi scoring method was used to compare the diagnostic value of parotid gland and submandibular gland scintigraphy for Sjögren's syndrome (SS).Methods Parotid gland and submandibular gland scintigraphy were conducted in 124 SS patients and 91 control subjects respectively, the results of scintigraphy of each gland were evaluated by excretion rate and 0-3 points per gland, the diagnostic accuracy of parotid and submandibular gland scintigraphy was compared by receiver operating characteristic curve (ROC).Results The score of parotid scintigraphy was 0-6, with the cut-off value of 2, the sensitivity for diagnosis of SS was 76.9%, the specificity was 72.6%, the area under the curve (AUC) was (0.798±0.030). The score of submandibular scintigraphy was 0-6, with the cut-off value of 2. The sensitivity for diagnosis of SS was 78.0%, the specificity was 78.2%, the area of AUC was 0.854±0.026.Conclusion The diagno-stic value of the submandibular gland scintigraphy is good.

关 键 词：腮腺 颌下腺 核素显像 干燥综合征 

分 类 号：R593.2[医药卫生—内科学] R817.4[医药卫生—临床医学]