多囊卵巢综合征中抗米勒管激素的作用  

The role of anti-Müllerian hormone in polycystic ovary syndrome

作　　者：张益倬 张跃辉[1] 韩延华[1] 王丽晶[2] 刘畅[2] 张蛟[3] ZHANG Yizhuo;ZHANG Yuehui;HAN Yanhua;WANG Lijing;LIU Chang;ZHANG Jiao(the First Department of Gynaecology,the First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin,Heilongjiang 150040,P.R.China;Department of Obstetrics and Gynecology,the First Hospital of Harbin,Harbin,Heilongjiang 150010,P.R.China;Traditional Chinese Medicine Hall,the Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine,Harbin,Heilongjiang 150001,P.R.China)

机构地区：[1]黑龙江中医药大学附属第一医院妇一科,哈尔滨150040 [2]哈尔滨市第一医院妇产科,哈尔滨150010 [3]黑龙江中医药大学附属第二医院国医堂,哈尔滨150001

出　　处：《华西医学》2020年第11期1399-1403,共5页West China Medical Journal

基　　金：国家自然科学基金(81774136);博士后研究人员落户黑龙江科研启动资助项目(LBH-Q17163);黑龙江中医药大学杰出青年基金培育项目;黑龙江中医药大学“优秀青年学术带头人”科研项目;韩延华全国名老中医药专家传承工作室建设项目。

摘　　要：多囊卵巢综合征是近年来女性常见的生殖内分泌疾病之一。大量研究发现多囊卵巢综合征患者的血清抗米勒管激素水平相比正常女性明显升高,尤其是无排卵型多囊卵巢综合征患者。该文简要介绍了多囊卵巢综合征病理表现中卵泡发育、高雄激素血症、肥胖和胰岛素抵抗等与抗米勒管激素的关系,以及多囊卵巢综合征患者中抗米勒管激素在辅助生殖、卵巢储备和诊断方面的应用,旨在为将抗米勒管激素更好地用于多囊卵巢综合征的诊治提供依据。Polycystic ovary syndrome is one of the common reproductive endocrine diseases in women in recent years.A large number of studies have found that serum anti-Müllerian hormone levels in patients with polycystic ovary syndrome are significantly higher than those in normal women,especially in anovulatory patients with polycystic ovary syndrome.This article briefly introduces the relationship between follicular development,hyperandrogenemia,obesity,and insulin resistance in the pathological manifestations of polycystic ovary syndrome and anti-Müllerian hormone,and the application of anti-Müllerian hormone in assisted reproduction,ovarian reserve and diagnosis in patients with polycystic ovary syndrome.It aims to provide a basis for better use of anti-Müllerian in the diagnosis and treatment of polycystic ovary syndrome.

关 键 词：抗米勒管激素 多囊卵巢综合征 卵泡发育 

分 类 号：R711.75[医药卫生—妇产科学]