氧驱雾化吸入普米克令舒治疗小儿哮喘急性发作的疗效及对肺功能改善作用研究  

Study on the efficacy of oxygen-driven atomized inhalation of Pulmicort in the treatment of acute attacks of childhood asthma and the improvement of lung function

作　　者：刘浩书 LIU Hao-shu(Department of Pediatrics,Benxi Central Hospital,Benxi 117000,China)

机构地区：[1]本溪市中心医院儿科,117000

出　　处：《中国实用医药》2020年第33期82-84,共3页China Practical Medicine

摘　　要：目的探究氧驱雾化吸入用布地奈德混悬液(商品名:普米克令舒)治疗小儿哮喘急性发作的疗效级对肺功能的改善效果。方法64例小儿哮喘急性发作患儿,随机分为对照组和观察组,每组32例。对照组接受常规治疗,观察组接受氧驱雾化吸入普米克令舒治疗。比较两组患儿临床疗效及肺功能指标[第1秒用力呼气容积(FEV1)、最大呼气流速(PEF)、用力肺活量(FVC)]。结果对照组患儿治疗总有效率为71.88%,观察组患儿治疗总有效率为93.75%;观察组患儿治疗总有效率显著高于对照组,差异有统计学意义(P<0.05)。观察组FEV1、PEF、FVC水平分别为(2.44±0.39)L、(192.63±24.52)L/min、(3.14±0.63)L,均显著优于对照组的(2.04±0.26)L、(175.68±25.60)L/min、(2.41±0.54)L,差异有统计学意义(P<0.05)。结论针对小儿哮喘急性发作患儿,临床给予氧驱雾化吸入普米克令舒治疗效果十分确切,亦可有效改善患儿的肺部功能,值得推荐。Objective To investigate the efficacy of oxygen-driven atomized inhalation of budesonide suspension for inhalation(trade name:Pulmicort)in the treatment of acute attacks of childhood asthma and the improvement of lung function.Methods A total of 64 children with acute attacks of asthma were randomly divided into control group and observation group,with 32 cases in each group.The control group was treated with conventional therapy,and the observation group was treated with oxygen-driven atomized inhalation of budesonide suspension for inhalation.The clinical efficacy,lung function indexes[forced expiratory volume in the first second(FEV1),peak expiratory flow(PEF),forced vital capacity(FVC)]were compared between the two groups.Results The total effective rate of treatment of the control group was 71.88%,which was 93.75%of the observation group.The total effective rate of treatment of the observation group was significantly higher than that of the control group,and the difference was statistically significant(P<0.05).The levels of FEV1,PEF and FVC of the observation group were(2.44±0.39)L,(192.63±24.52)L/min and(3.14±0.63)L,which were significantly better than(2.04±0.26)L,(175.68±25.60)L/min and(2.41±0.54)L of the control group,and the difference was statistically significant(P<0.05).Conclusion Oxygen-driven atomized inhalation of Pulmicort has affirmative clinical effect’for children with acute attacks of asthma,and it can also effectively improve the lung function of children.It is worth recommending.

关 键 词：氧驱雾化吸入 吸入用布地奈德混悬液 小儿哮喘急性发作 肺功能 

分 类 号：R725.6[医药卫生—儿科]