金纳米三角片滤纸基底膜的制备及对食品污染物的快速检测  

Preparation of Base Membrane of Gold Nanotriangle Filter Paper and Its Application in Rapid Detection of Food Contaminants

作　　者：王娟 周亚茹 汪倩倩 李曼 栾龙龙 张祥 徐维平 WANG Juan;ZHOU Ya-Ru;WANG Qian-Qian;LI Man;LUAN Long-Long;ZHANG Xiang;XU Wei-Ping(College of Pharmacy,Anhui University of Chinese Medicine,Hefei 230012,China;College of Chemistry and Chemical Engineering,Hefei University of Technology,Hefei 230009,China;Department of Life Sciences and Medicine,University of Science and Technology of China,Hefei 230026,China;The First Affiliated Hospital of University of Science and Technology of China,Hefei 230001,China)

机构地区：[1]安徽中医药大学药学院,合肥230012 [2]合肥工业大学化学与化工学院,合肥230009 [3]中国科学技术大学生命科学与医学部,合肥230026 [4]中国科学技术大学附属第一医院,合肥230001

出　　处：《分析化学》2020年第12期1625-1632,共8页Chinese Journal of Analytical Chemistry

基　　金：国家自然科学基金项目(No.51672004);安徽省自然科学基金项目(No.1608085MH176);安徽省科技攻关项目(No.1804h08020252)资助。

摘　　要：利用滤纸的毛细管效应结合表面增强拉曼光谱(SERS)技术的快速检测功能,制备了SERS多功能基底感应卡。首先将合成的金纳米三角片利用液-液界面自组装法制备大面积致密的纳米膜,然后将其转移至滤纸表面作为SERS基底膜。以结晶紫(CV)作为拉曼探针分子,此基底膜具有较好的SERS灵敏度和重复性。利用此基底膜检测了白酒中的塑化剂邻苯二甲酸卞酯(BBP)、果皮表面的噻苯咪唑(TBZ)和鱼类表面的抗生素孔雀石绿(MG)。结果表明,此基底膜对BBP、TBZ和MG的检测浓度可低至1×10^-8 mol/L,检测速度快、灵敏度高、操作便捷,具有良好的SERS分析潜力。Food safety is closely related with human life and health,therefore,it is particularly necessary to establish a fast,sensitive,simple and convenient testing means for food contaminants.Surface-enhanced Raman spectroscopy(SERS)has the characteristics of quickness,convenience and high sensitivity for the field detection and analysis of food contaminants.In this work,the capillary effect of filter paper combined with the quick detection function of SERS technology was used to prepare SERS multi-functional base sensor cards.Firstly,a large area of dense nano membrane was prepared by using the self-assembly method of liquid-liquid interface with the synthesized gold nanotriangle,which was transferred to the surface of filter paper as SERS base membrane.Crystal violet(CV)was used as the Raman probe molecule to investigate SERS sensitivity and repeatability of the substrate membrane,and the plasticizer benzyl butyl phthalate(BBP)in liquor,thiabendazole(TBZ)on the peel surface and antibiotic malachite green(MG)on the fish surface were also detected.The results showed that the concentration of BBP,TBZ and MG could be detected at 1×10^-8 mol/L.This kind of SERS substrate membrane showed a fast detection speed,high sensitivity,convenient operation,and a great potential for SERS analysis.

关 键 词：金纳米三角片 液-液界面自组装 滤纸基底 表面增强拉曼光谱 食品污染物 

分 类 号：O657.37[理学—分析化学] TS207.5[理学—化学]