2017~2019年唐山工人医院过敏性疾病过敏原检测分析  

Analysis of Allergen Detection of Allergic Diseases in Tangshan Workers Hospital from 2017 to 2019

作　　者：卢家兴 陈昭[2] LU Jia-xing;CHEN Zhao(North China University ofScience and Technology,Tangshan 063000,Hebei,China;Department of Dermatology and Venereology,Tangshan Workers'Hospital,Tangshan 063000,Hebei,China)

机构地区：[1]华北理工大学,河北唐山063000 [2]唐山工人医院皮肤性病科,河北唐山063000

出　　处：《医学信息》2020年第23期125-128,共4页Journal of Medical Information

摘　　要：目的分析2017~2019年唐山工人医院5134例过敏性疾病患者的常见过敏原及其流行病学特征。方法收集2017年1月~2019年9月于我科门诊就诊的5134例过敏性疾病患者的临床资料,应用变应原特异性IgE抗体检测试剂盒检测患者血清中的14种变应原sIgE抗体,分析过敏源分布情况。结果5134例过敏性疾病患者一种过敏原呈阳性反应占28.32%;总IgE阳性率为86.54%,sIgE阳性率为52.35%;吸入性过敏原以户尘螨/粉尘螨(20.17%)为主,食入性过敏原以鸡蛋白(13.67%)、牛奶(13.65%)为主;食入性过敏原阳性率(34.53%)高于吸入性(31.98%);男性患者过敏原检出率高于女性;0~18岁、19~35岁、>35岁患者最主要的过敏原分别为牛奶、尘螨/粉尘螨;每个季度吸入性过敏原阳性率均高于食入性,且以尘螨为主,第三季度过敏患者最多;湿疹患者的过敏性检出率最高,其次为荨麻疹、过敏性紫癜。结论该院过敏性疾病患者的过敏原以户尘螨/粉尘螨、鸡蛋白、牛奶为主,不同性别、年龄、季度及病种的过敏原分布存在一定差异。Objective To analyze the common allergens and their epidemiological characteristics of 5134 patients with allergic diseases in Tangshan Workers'Hospital from 2017 to 2019.Methods The clinical data of 5134 patients with allergic diseases who visited our department from January 2017 to September 2019 were collected,and the allergen-specific IgE antibody detection kit was used to detect 14 kinds of allergen sIgE antibodies in the patients'serum,analyze the distribution of allergens.Results 28.32%of 5134 patients with allergic diseases were positive for one allergen;the total IgE positive rate was 86.54%,and the sIgE positive rate was 52.35%;the inhaled allergens were house dust mites/dust mites(20.17%).Ingested allergens are mainly egg white(13.67%)and milk(13.65%);the positive rate of ingested allergens(34.53%)is higher than that of inhaled ones(31.98%);the detection rate of allergens in male patients is higher Female;the most important allergens for patients aged 0-18,19-35,and>35 are milk,dust mites/dust mites;the positive rate of inhaled allergens is higher than that of ingested,and dust mite is the main disease,with the most allergic patients in the third quarter;the allergic detection rate of eczema patients is the highest,followed by urticaria and allergic purpura.Conclusion The allergens of patients with allergic diseases in this hospital are mainly house dust mites/dust mites,chicken albumen,and milk.There are certain differences in the distribution of allergens in different genders,ages,seasons and disease types.

关 键 词：过敏性疾病 特异性IGE 过敏原 

分 类 号：R725.9[医药卫生—儿科] R446.6[医药卫生—临床医学]