葡萄酒色斑的光动力治疗进展  

Research in Photodynamic Therapy for Port-Wine Stains

作　　者：张玙嫣 马刚[1] 林晓曦[1] ZHANG Yu-yan;MA Gang;LIN Xiao-xi(Department of Plastic and Reconstructive Surgery,Shanghai Ninth People's Hospital,Shanghai University School of Medicine,Shanghai 200011,China)

机构地区：[1]上海交通大学医学院附属第九人民医院,上海市200011

出　　处：《中国激光医学杂志》2020年第5期266-273,共8页Chinese Journal of Laser Medicine & Surgery

基　　金：国家百千万人才工程项目;上海市领军人才项目;上海市优秀学科带头人计划资助。

摘　　要：葡萄酒色斑(port-wine stains,PWS)又称鲜红斑痣,是发病率最高的血管畸形。目前的一线治疗方案为脉冲染料激光(pulsed dye laser,PDL),然其疗效不尽如人意。自从20世纪90年代我国将光动力治疗(Photodynamic therapy,PDT)运用于葡萄酒色斑后,显著提高了PWS治疗效果。本文就近年来葡萄酒色斑的PDT进展进行阐述,包括其可能的机制、疗效、影响因素与判定手段等。Port-wine stains(PWS),also known as nevus flammeus,is the most prevalent vascular malformation.At present,despite of unsatisfying efficacy,pulsed dye laser(PDL)is used as a standard therapy for PWS.Photodynamic therapy(PDT)has significantly improved the therapeutic effect of PWS since it was introduced to treat PWS in China in the 1990 s.This paper reviews the progress of PDT for PWS in recent years,including the possible mechanisms,factors influencing the therapeutic effect and the means measuring the efficacy.

关 键 词：葡萄酒色斑 光动力治疗 激光 

分 类 号：R454.3[医药卫生—治疗学] R751[医药卫生—临床医学]