黄褐斑治疗2020年最新进展  

Update of Melasma Treatment in 2020

作　　者：罗瑶佳 李远宏[2,3] LUO Yao-jia;LI Yuan-hong(Department of Dermatology,Shenzhen Distinct Clinic,shenzhen 51800,China;Yanyue Cosmetic Dermatology Clinic;Department of Dermatology,No.1 Hospital of China Medical University)

机构地区：[1]卓正医疗皮肤科,深圳市518000 [2]沈阳颜悦医美 [3]中国医科大学附属第一医院皮肤科

出　　处：《中国激光医学杂志》2020年第5期274-280,共7页Chinese Journal of Laser Medicine & Surgery

基　　金：2018年中华医学会-欧莱雅中国人健康皮肤/毛发研究项目(H2018151107)。

摘　　要：黄褐斑是后天获得性色素代谢异常性疾病,主要表现为面部等曝光部位对称性的棕色或灰棕色不规则形不良反应。外用药物、化学剥脱、口服药物都是黄褐斑的常规治疗手段,但是对于难治性黄褐斑,治疗效果不佳,复发率高,需要使用光电治疗等其他辅助手段。目前最常见的光电治疗手段包括强脉冲光、低强度调Q激光、非剥脱点阵激光等,这些方法都有一定效果,但有一定复发率,也有增加色素沉着或者色素减退的风险。近年来,皮秒激光、点阵射频激光、激光辅助药物传输等逐渐用于黄褐斑的治疗,为此笔者检索了Pub Med,Web of Science,Embase和Cochrane数据库2020年1~6月发表和收录的关于黄褐斑最新文献,综述了关于黄褐斑治疗的最新观点。Melasma is an acquired hyperpigmentation disease characterized by symmetric,brownish-gray irregular macules and patches on the sun-exposed area.Topical medication,chemical peeling,oral medications are conventional treatment for melasma,but treatment effect in recalcitrant cases is limited.Laser and light-based therapies have become an alternative approach.Intense pulsed light(IPL),low energy Q-switched,non-ablative fractionated laser may achieve satisfactory result,with the risk of recurrence and hyper/hypo-pigmentation in long-term effects.Picosecond lasers,fractionated radiofrequency,and laser-assisted drug delivery are gaining more important roles as adjuvant methods.Database of Pubmed,Web of Science,Embase and Cochrane were searched for melasma paper published in January to June of 2020,latest updated treatment protocols are reviewed in this paper.

关 键 词：黄褐斑 光电治疗 药物传输 

分 类 号：K318.51[历史地理—历史学] R751[历史地理—世界史]