中药防治新型冠状病毒肺炎机制的研究进展  

Mechanism of Preventing and Treating COVID-19 with Traditional Chinese Medicine

作　　者：陶嘉磊[1] 林丽丽[1] 沈存思[1] 谢彤[1] 赵霞[1] 汪受传[1] 单进军[1] 纪建建 TAO Jia-lei;LIN Li-li;SHEN Cun-si;XIE Tong;ZHAO Xia;WANG Shou-chuan;SHAN Jin-jun;JI Jian-jian(Jiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatrics, Nanjing University of Chinese Medicine, Nanjing, 210023, China)

机构地区：[1]南京中医药大学中医儿科学研究所,江苏省儿童呼吸疾病(中医药)重点实验室,江苏南京210023

出　　处：《南京中医药大学学报》2020年第6期902-906,共5页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏省自然科学基金(BK20180825,BK20190808);全国名中医工作室建设项目(国中医药办人教函〔2018〕119号);江苏省卫生健康委员会医学科研项目(Z2018003);江苏省高校自然科学基金(19KJB360002,19KJB360010);国家自然科学基金青年基金(81904029)。

摘　　要：以清肺排毒汤为代表的中药方剂能够显著改善新型冠状病毒肺炎(COVID-19)患者症状、缩短病程、延缓疾病进展、减少重症转化率、降低死亡率,在此次新冠疫情防治中发挥了重要作用。结合COVID-19病理生理特征,在总结COVID-19潜在发病机制基础上,从直接抗病毒、调节免疫作用、缓解肺损伤与清除痰栓等方面对中药防治COVID-19的潜在机制进行了综述,以期为中药防治COVID-19的科学研究提供借鉴。The prescription of traditional Chinese medicine(TCM)represented by Qingfei Paidu Decoction played an important role in the prevention and treatment of COVID-19.Treatment practice of COVID-19 showed that early intervention of TCM was considerable in improving the cure rate,shortening the course,delaying disease progression,and reducing mortality rate,but the mechanisms were unclear.Based on the pathophysiological characteristics of current COVID-19 patients,we summarized the potential pathogenesis of COVID-19,which would be helpful in research of TCM against COVID-19.

关 键 词：中医药 新型冠状病毒肺炎 肺损伤 免疫损伤 

分 类 号：R254.3[医药卫生—中医内科学]