某院老年急性胰腺炎患者医院感染特点及其危险因素分析  

Analysis of characteristics and risk factors of nosocomial infection in elderly patients with acute pancreatitis

作　　者：邢芳芳 廖鸿俊 邢颖[1] 周建红 薛珊 XING Fang-fang;LIAO Hong-jun;XING Ying;ZHOU Jian-hong;XUE Shan(Hospital of the 72 th Group Army,PLA,Huzhou Zhejiang 313000,China)

机构地区：[1]中国人民解放军第72集团军医院,浙江湖州313000

出　　处：《中国消毒学杂志》2020年第10期771-773,777,共4页Chinese Journal of Disinfection

摘　　要：目的分析老年急性胰腺炎(AP)患者医院感染特点及其危险因素,为开展干预措施提供依据。方法回顾性收集2012年1月至2018年12月某院消化内科老年AP患者临床基线资料,分析感染患者临床特点及其危险因素。结果共收集老年AP患者206例,发生感染76例,感染率为36.89%。感染部位以下呼吸道、腹腔感染为主,分别占38.55%、31.33%。感染部位检出的102株病原菌中革兰阴性菌、革兰阳性菌以及真菌分别占70.59%、26.47%、2.94%,革兰阴性菌分布以铜绿假单胞菌检出率排首位,革兰阳性菌以金黄色葡萄球菌检出率最高。多因素分析结果显示,低氧血症、入住ICU、APACHEII≥8分、糖尿病是老年AP患者发生感染的独立危险因素(P<0.05)。结论老年AP患者医院感染率较高,检出病原菌主要以革兰阴性杆菌为主,多种因素与其感染发生密切相关,医务人员应当及时采取有针对性的感染防控措施。Objective To analyze the characteristics and risk factors of nosocomial infection in elderly patients with acute pancreatitis(AP),and provide a basis for intervention measures.Methods The clinical baseline data of elderly AP patients in the gastroenterology department of a hospital from January 2012 to December 2018 were retrospectively collected,and the clinical characteristics and risk factors of infected patients were analyzed.Results A total of 206 elderly AP patients were enrolled,and 76 cases were infected with an infection rate of 36.89%.Lower respiratory tract and abdominal cavity infections were the main infection sites,accounting for 38.55%and 31.33%,respectively.Among 102 strains of pathogenic bacteria detected at the site of infection,Gram-negative bacteria,Gram-positive bacteria and fungi accounted for 70.59%,26.47%,and 2.94%,respectively.Among the Gram-negative bacteria,the detection rate of Pseudomonas aeruginosa was ranked first,and among the Gram-positive bacteria,the detection rate of Staphylococcus aureus was the highest.Multivariate analysis showed that hypoxemia,ICU admission,APACHE II≥8 points,and diabetes were independent risk factors for infection in elderly AP patients(P<0.05).Conclusion The nosocomial infection rate of elderly AP patients was relatively high.The main pathogens detected were Gram-negative bacilli,and many factors were closely related to infection.Medical staff should take timely targeted infection prevention and control measures.

关 键 词：老年患者 急性胰腺炎 医院感染 危险因素 

分 类 号：R446.5[医药卫生—诊断学]