伊维菌素耐药及敏感捻转血矛线虫国内分离株的鉴定  

Identification of Ivermectin-resistant Strain and Sensitive Strain of Haemonchus contortus in China

作　　者：罗晓平 王鹏龙[2] 李军燕 杨晓野 耿万恒[1] 高娃 白宝霞 赵世华 LUO Xiao-ping;WANG Peng-long;LI Jun-yan;YANG Xiao-ye;GENG Wan-heng;Gaowa;BAI Bao-xia;ZHAO Shi-hua(Inner Mongolia Academy of Agricultural and Animal Husbandry Sciences,Hohhot010031,China;Inner Mongolia Agricultural University,Hohhot010018,China;Animal Husbandry and Veterinary Medicine Station of Baogedewula Sumu of New Barag Right Banner,New Barag Right Banner021300,China)

机构地区：[1]内蒙古自治区农牧业科学院,内蒙古呼和浩特010031 [2]内蒙古农业大学,内蒙古呼和浩特010018 [3]新巴尔虎右旗宝格德乌拉苏木畜牧兽医站,内蒙古新巴尔虎右旗021300

出　　处：《畜牧与饲料科学》2020年第6期94-99,共6页Animal Husbandry and Feed Science

基　　金：内蒙古自治区农牧业青年创新基金项目(2017QNJJM05);国家自然科学基金项目(31660710);内蒙古自治区农牧业创新基金项目(2020CXJJM06)。

摘　　要：为解决国内开展驱虫药耐药性相关研究中虫种资源缺乏问题,该研究采用国际通用方法开展了华北地区捻转血矛线虫耐伊维菌素虫株的分离工作,并采用传统形态学方法对其进行鉴定。对来源不同的耐伊维菌素捻转血矛线虫虫株进行分离,结果显示:华北地区分离到了4株对伊维菌素6倍耐药及1株对其敏感的捻转血矛线虫。该研究将为国内开展捻转血矛线虫耐伊维菌素研究及新型驱虫药物的开发提供虫种资源。In order to solve the problem of lacking species resources in the domestic research on the resistance of anthelmintic drugs,this study used international common methods to isolate the ivermectin-resistant strains of Haemonchus contortus in north China,and adopted traditional morphologic method to identify them.Ivermectin-resistant Haemonchus contortus strains from different sources in north China were isolated,and the results showed that 4 strains of Haemonchus contortus were 6 times resistant to ivermectin and 1 strain was susceptible.This research provide species resources for domestic research on ivermectin resistance of Haemonchus contortus and the development of new anthelmintic drugs.

关 键 词：捻转血矛线虫 伊维菌素 耐药 分离 鉴定 

分 类 号：S859.795[农业科学—临床兽医学] S852.731[农业科学—兽医学]