柴胡消渴汤联合胰岛素治疗糖尿病胰岛素抵抗临床观察  

Clinical Observation of Chaihu Xiaoke Decoction combined with Insulin in Treating Diabetic Insulin Resistance

作　　者：刘振洲 韩艳茹 任伟华[1] 贾奎[1] LIU Zhenzhou;HAN Yanru;REN Weihua;JIA Kui(The First Affilliaded Hospital of Xinxiang Medicine College,Weihui 453100,Henan,China)

机构地区：[1]新乡医学院第一附属医院,河南卫辉453100

出　　处：《实用中医内科杂志》2020年第11期49-51,共3页Journal of Practical Traditional Chinese Internal Medicine

基　　金：河南省医学教育研究项目(2013KY173)。

摘　　要：目的对糖尿病患者采取柴胡消渴汤治疗,对其治疗效果进行研究分析。方法研究对象选自医院2018年4月-2019年4月100例糖尿病患者。采取随机数字表法分为两组,分别为治疗组和对照组,两组各50例。治疗组采取柴胡消渴汤联合皮下注射胰岛素治疗。对照组采取皮下注射胰岛素治疗(甘精胰岛素;门冬胰岛素)。对两组治疗效果进行观察,比较两组空腹血糖、饭后2 h血糖、胰岛素抵抗指数以及不良反应发生率。结果两组经治疗后,治疗组空腹血糖(7.32±0.32)、饭后2 h血糖(9.36±1.21)均低于对照组空腹血糖(9.67±1.23)、饭后2 h血糖(12.34±1.37),两组间比较,差异具有统计学意义(P<0.05)。治疗组胰岛素抵抗指数优于对照组(P<0.05)。治疗组不良反应发生率低于对照组(P<0.05)。结论此次研究中,对糖尿病患者采取柴胡消渴汤治疗,其治疗后可达到预期效果。能有效降低空腹血糖以及饭后2 h血糖。并且能够较好的改善胰岛素抵抗指数。该治疗方法有着较高的安全性。可降低不良反应的发生。柴胡消渴汤可在糖尿病患者治疗中予以推广应用。Objective In this study,Chaihu Xiaoke decoction was used to treat diabetic patients,and the therapeutic effect was studied and analyzed.Method The study is connected to the selected hospital in April 2018 to April 2019100 cases of diabetes.The above patients were divided into two groups by random number table method.They are the experimental group and the routine group.There were 50 patients in each group.Patients in the experimental group were treated with Chaihu Xiaoke decoction combined with subcutaneous insulin injection.Patients in the routine group were treated with subcutaneous insulin injections(insulin glargine;insulin aspart).The two groups were observed therapeutic effects were compared fasting glucose,glucose 2 hours after a meal,insulin resistance index and the incidence of adverse reactions.Results After treatment in the two groups,the fasting blood glucose(7.32±0.32)and 2-hour blood glucose(9.36±1.21)of the experimental group were lower than those of the conventional group(9.67±1.23)and 2-hour blood glucose(12.34±1.37),between the two groups that satisfy the difference was statistically significant(P<0.05).The insulin resistance index of the experimental group was better than that of the conventional group(P<0.05).The incidence of adverse reactions in the experimental group was lower than that in the control group.The difference between the two groups was statistically significant(P<0.05).Conclusion In this study,the treatment of diabetic patients with Chaihu Xiaoke decoction can achieve the expected effect after treatment.Can effectively reduce fasting blood sugar and blood sugar 2 hours after meals.And better able to improve insulin resistance index.This treatment method has high safety.Can reduce the occurrence of adverse reactions.Chaihu Xiaoke decoction can be promoted and applied in the treatment of diabetic patients.

关 键 词：柴胡消渴汤 糖尿病 胰岛素 空腹血糖 饭后2 h血糖 抵抗指数 不良反应 安全性 

分 类 号：R255.4[医药卫生—中医内科学]