广州地区体检人群维生素D水平分析  

Analysis of vitamin D level in people taking physical examination in Guangzhou

作　　者：谢洁雯 魏秋静[1] 吴中鸣 古洁若[1] Xie Jiewen;Wei Qiujing;Wu Zhongming;Gu Jieruo(Rheumatology and Immunology Department,The Third Affiliated Hospital,SunYat-senUniversity,Guangzhou 510000,China)

机构地区：[1]中山大学附属第三医院风湿科,广州510620

出　　处：《中华临床实验室管理电子杂志》2020年第4期224-227,共4页Chinese Journal of Clinical Laboratory Management(Electronic Edition）

摘　　要：目的对广州地区体检人群25羟基维生素D[25(OH)D]检查结果进行分析,了解各类人群25(OH)D水平状况,辅助诊断因维生素D缺乏引起的相关疾病。方法使用化学发光法测定2016年1月至2019年1月共9163例体检者血清25(OH)D水平,分别比较不同性别、年龄人群25(OH)D营养水平。结果9163例体检者血清25(OH)D的平均水平为63.89 nmol/L,正常率为26.41%,不足率为46.45%,缺乏率为27.14%。男性25(OH)D总体正常率为29.29%,不足率为47.36%,缺乏率为23.28%;女性25(OH)D总体正常率为23.26%,不足率为45.42%,缺乏率为31.32%。女性群体25(OH)D缺乏率高于男性,差异有统计学意义(P=0.000)。男女体检群体中25(OH)D缺乏率最高的均为20岁~29岁年龄段,分别为28.75%、42.71%。对不同月份维生素D水平进行分析,发现血清25(OH)D水平最高为5月,最低为2月。结论广州地区人群存在不同程度的25(OH)D缺乏,且女性相比男性有更高的缺乏率。Objective The aim of this study was to help diagnose diseases caused by Vitamin D deficiency by analyzing the 25-hydroxyvitamin D[25(OH)D]level in people taking physical examination in Guangzhou.Methods The serum 25(OH)D levels were determined by chemiluminescent assayin 9163 physical examination subjects from January 2016 to January 2019,and 25(OH)D nutritional levels were compared among different genders and age groups.Results Mean serum 25(OH)D level of 9163 subjects was 63.89 nmol/L.Subjects with adequate,inadequate and deficient serum 25(OH)D took percentage of 26.41%,46.45%and 27.14%,respectively.Male subjects with adequate,inadequate and deficient serum 25(OH)D took percentage of 29.29%,47.36%and 23.28%,respectively.Female subjects with adequate,inadequate and deficient serum 25(OH)D took percentage of 23.26%,45.42%and 31.32%,respectively.Serum 25(OH)D deficiency in female subjects was higher than that in male subjects.The difference in this study has statistical significance(P=0.000).The highest 25(OH)D deficiency rate in male and female physical examination groups were in the 20~29 age group(28.75%and 42.71%,respectively).Analysis on vitamin D levels in different months indicated that the highest level of serum 25(OH)D appears in May,while the lowest appears in February.Conclusion There are different levels of 25(OH)D deficiency in people living Guangzhou,and women have a higher rate of deficiency than men.

关 键 词：25羟基维生素D 维生素D缺乏率 体检人群 

分 类 号：R194.3[医药卫生—卫生事业管理]