31例肥胖合并2型糖尿病患者减重手术后的血糖分析  

Analysis on blood glucose after weight-loss surgery in 31 obese patients with type 2 diabetes mellitus

作　　者：吕金娥 李滢旭 雷志辉 李娅萍 张丽晶 陶然 赵丽红 戴宏斌 Lyu Jin'e;Li Yingxu;Lei Zhihui;Li Yaping;Zhang Lijing;Tao Ran;Zhao Lihong;Dai Hongbin(Clinical Laboratory,Qujing Second People's Hospital,Qujing 655000,Yunnan,China;Department of Hepatobiliary,Qujing Second People's Hospital,Qujing 655000,Yunnan,China)

机构地区：[1]曲靖市第二人民医院检验科,云南曲靖655000 [2]曲靖市第二人民医院肝胆一科,云南曲靖655000

出　　处：《实用检验医师杂志》2020年第4期221-223,共3页Chinese Journal of Clinical Pathologist

摘　　要：目的探讨减重手术对肥胖合并2型糖尿病(T2DM)患者空腹血糖(FBG)和糖化血红蛋白(HbA1c)水平的影响。方法回顾性分析2014年6月—2019年8月于曲靖市第二人民医院接受减重手术的31例肥胖合并T2DM患者的临床资料,记录所有患者术前和术后1、3、6、12个月的体质量、体质量指数(BMI)、FBG、HbA1c,分析并比较上述指标的变化。结果31例肥胖合并T2DM患者减重手术后1、3、6、12个月的体质量和BMI均较术前明显下降〔体质量(kg):79.36±17.60、73.11±12.47、69.26±9.41、67.47±8.18比88.60±18.84,BMI(kg/m2):29.29±4.67、26.27±2.45、24.93±1.86、24.28±1.39比32.31±5.20,均P<0.01〕,且随时间延长呈逐渐下降趋势,于术后12个月达到最低;31例肥胖合并T2DM患者减重手术后有28例FBG水平明显下降,占90.3%。术后1、3、6、12个月的FBG和HbA1c较术前均明显降低〔FBG(mmol/L):6.42±1.80、6.39±1.92、6.37±2.11、6.14±1.65比9.80±3.32,HbA1c:0.068±0.009、0.063±0.009、0.061±0.008、0.057±0.006比0.084±0.015,均P<0.01〕,且随时间延长呈逐渐下降趋势,于术后12个月达到最低。结论减重手术对降低肥胖合并T2DM患者FBG和HbA1c的作用显著,近期治疗效果明显,可以在临床推广。Objective To investigate the effect of weight-loss surgery on fasting blood glucose(FBG)and glycosylated hemoglobin(HbA1c)levels in obese patients with type 2 diabetes mellitus(T2DM).Methods The clinical data of 31 patients with obesity complicated with T2DM after weight-loss surgery in Qujing Second People's Hospital from June 2014 to August 2019 were retrospectively analyzed.The body mass,body mass index(BMI),FBG and HbA1c of the patients were statistically recorded before and after 1,3,6 and 12 months of operation,and the above indexes were analyzed and compared.Results The body mass and BMI of 31 obese patients with T2DM at 1,3,6 and 12 months after operation were lower than those before operation[body mass(kg):79.36±17.60,73.11±12.47,69.26±9.41,67.47±8.18 vs.88.60±18.84,BMI(kg/m2):29.29±4.67,26.27±2.45,24.93±1.86,24.28±1.39 vs.32.31±5.20,all P<0.01],gradually decreased with time,and reached the lowest at 12 months.Among 31 obese patients with T2DM after weight-loss surgery,FBG decreased significantly in 28 patients,accounting for 90.3%.FBG and HbA1c at 1,3,6 and 12 months after surgery were lower than those before surgery[FBG(mmol/L):6.42±1.80,6.39±1.92,6.37±2.11,6.14±1.65 vs.9.80±3.32,HbA1c:0.068±0.009,0.063±0.009,0.061±0.008,0.057±0.006 vs.0.084±0.015,all P<0.01],gradually decreased with time,and reached the lowest at 12 months after surgery.Conclusion Weight-loss surgery has a significant effect on reducing FBG and HbA1c in obese patients with T2BM,and the short-term treatment effect is obvious,which can be promoted in clinical practice.

关 键 词：2型糖尿病 减重手术 空腹血糖 糖化血红蛋白 分析 

分 类 号：R656.61[医药卫生—外科学]