弥散加权成像在前列腺癌诊断与鉴别诊断中的应用价值  

The Application Value of Diffusion Weighted Imaging in the Diagnosis and Differential Diagnosis of Prostate Cancer

作　　者：程茂军 蒋会东[1] 李军[1] 翟松林 刘文景[1] CHENG Mao-Jun;JIANG Hui-Dong;LI Jun;ZHAI Song-lin;LIU Wen-jing(Department of Imaging,The First People's Hospital of Chuzhou City,Chuzhou 239000,Anhui Province,China)

机构地区：[1]滁州市第一人民医院影像科,安徽滁州239000

出　　处：《中国CT和MRI杂志》2021年第1期147-148,151,共3页Chinese Journal of CT and MRI

基　　金：滁州市科技计划项目(2018ZD012)。

摘　　要：目的探讨弥散加权成像(diffusion-weighted imaging,DWI)在前列腺癌(prostatic cancer,PC)诊断与鉴别诊断中的应用价值。方法病例源于2015年12月至2018年12月我院收治的94例疑似PC患者,均行T2WI、DWI扫描检查,评估DWI在PC诊断中的效能,并比较PC组、良性前列腺增生(benign prostatic hyperplasia,BPH)组表观弥散系数值、信号强度值相关参数。结果组织穿刺活检或手术病理证实94例疑似PC患者,共有64例为PC患者,30例BPH,DWI诊断PC的灵敏度为87.50%,特异度为73.33%,准确度为82.98%;PC组信号强度值、表观弥散系数值较BPH组明显低,差异有统计学意义(P<0.05)。结论DWI在PC诊断以及鉴别诊断中有明确应用价值。Objective To investigate the application value of diffusion-weighted imaging(DWI)in the diagnosis and differential diagnosis of prostate cancer(PC).Methods The cases were from 94 patients with suspected PC who were admitted to the hospital from December 2015 to December 2018.All patients underwent MRI DWI and a dynamic contrast-enhanced MRI scan.The diagnostic efficiency of MRI DWI in PC was evaluated.The apparent diffusion coefficient values,signal intensity values,and MRI contrast-enhanced scan related indexes in the PC group and bPH group were compared.ResultsThere were 94 cases with suspected PCconfirmed by tissue puncture and biopsy.There were 64 cases with PC and 30 cases with bPH.The sensitivity,specificity,and accuracy of DWI for diagnosis of PC were 87.50%,73.33%,and 82.98%,respectively.The signal intensity values and apparent diffusion coefficient values in the PC groupwere significantly lower than those in the bPH group(P<0.05).The Ktrans,percentage of the interstitial volume of the extravascular cell,and rate constants in the PC group were significantly higher than those in the bPH group(P<0.05).Conclusion The application value of DWI combined with dynamic contrast-enhanced MRI scan is obviousfor diagnosis and differential diagnosis of PC.

关 键 词：前列腺癌 弥散加权成像 鉴别诊断 应用价值 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.25[医药卫生—诊断学]