度洛西汀联合M受体拮抗剂治疗女性焦虑合并膀胱过度活动症的疗效  

作　　者：吴哲[1] 朱双阅 李瑞鹏[2] 

机构地区：[1]杭州市第七人民医院,310013 [2]杭州市第三人民医院,310009

出　　处：《浙江临床医学》2020年第11期1601-1602,共2页Zhejiang Clinical Medical Journal

摘　　要：目的探讨度洛西汀联合M受体拮抗剂治疗焦虑合并膀胱过度活动症(OAB)的临床疗效。方法选取60例女性焦虑合并膀胱过度活动症患者分为观察组与对照组各30例,观察组采用度洛西丁联合M受体拮抗剂治疗,对照组单纯使用M受体拮抗剂;治疗4周后比较两组尿急次数、日均排尿次数、夜尿次数、膀胱最大容量及治疗效果结果治疗4周后,观察组尿急次数、日均排尿次数、尿失禁次数、膀胱最大容量治疗效果均优于对照组,差异均有统计学意义(P<0.05)。结论度洛西汀联合M受体拮抗剂能在一定程度上缓解女性焦虑合并膀胱过度活动症患者的临床症状,提高治疗效果。Objective To explore the cinical efiacy of duloxeine combined with M reeptor anagonis in the treatment of anxiety complicated by overactive bladder.Methods 60 female anxiety patients with overactive bladder were divided into observation group and control group,30 cases each.The observation group was treated with duloxetine combined with M-body antagonist,and the control group was treated with M-receptor antagonist only.After 4 weeks of treatment,the number of urgency,average daily urination,nocturia,maximum bladder capacity,and treatment efect were compared between the two groups.Results After 4 weeks of trearment,the observation group had better urgency times,daily average urination times,urinary incontinence times,and maximum bladder volume treatment efects than the control group,and the differences were satistically significant(P<0.05).Conclusion Duloxetine combined with M receptor anagonists can alviate the clinical symptoms of female patients with anxiety complicated by overactive bladder to a certain extent and improve the treatment efect.

关 键 词：膀胱过度活动症 度洛西汀 M受体拮抗剂 女性 

分 类 号：R47[医药卫生—护理学]