强脊汤联合西医治疗强直性脊柱炎临床观察  被引量:2

Clinical observation of treating ankylosing spondylitis with Qiangji decoction combined with western medicine therapy

在线阅读下载全文

作  者:刘茜茜 闫起 李泽光[2] LIU Qianqian;YAN Qi;LI Zeguang(Heilongjiang University of Chinese Medicine,Heilongjiang,Harbin 150040;不详)

机构地区:[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江中医药大学附属第一医院风湿病科,黑龙江哈尔滨150040

出  处:《河北中医》2020年第8期1190-1193,1198,共5页Hebei Journal of Traditional Chinese Medicine

基  金:黑龙江省教育厅科学技术研究项目(编号:12531z011);黑龙江中医药大学新药研究基金资助项目(编号:Z201201)。

摘  要:目的观察强脊汤联合西医治疗强直性脊柱炎(AS)的临床疗效。方法将60例AS患者按照随机数字表法分为2组。对照组30例予西医常规治疗,治疗组30例在对照组基础上联合强脊汤治疗。2组均45 d为1个疗程,治疗2个疗程后统计疗效,比较2组治疗前后巴斯强直性脊柱炎疾病活动度指数(BASDAI)评分、巴斯强直性脊柱炎躯体功能指数(BASFI)评分、疼痛视觉模拟评分(VAS)及晨僵持续时间变化情况,比较2组治疗前后红细胞沉降率(ESR)及C反应蛋白(CRP)水平变化情况,比较2组治疗期间的不良反应发生情况。结果治疗组总有效率93.33%(28/30),不良反应发生率10.00%(3/30),对照组总有效率73.33%(22/30),不良反应发生率33.33.%(10/30),治疗组总有效率高于对照组(P<0.05),不良反应发生率低于对照组(P<0.05)。与本组治疗前比较,2组治疗后BASDAI评分、BASFI评分及疼痛VAS均明显降低(P<0.05),晨僵时间均明显减少(P<0.05),且治疗组各项指标改善均优于对照组(P<0.05)。与本组治疗前比较,2组治疗后ESR及CRP水平均明显降低(P<0.05),且治疗后治疗组ESR及CRP水平均低于对照组(P<0.05)。结论强脊汤联合西医治疗AS疗效确切,可明显改善患者临床症状、体征,缓解疼痛,缩短晨僵时间,抑制炎性反应,降低ESR及CRP水平,减少不良反应,具有减毒增效的作用。Objective To observe the clinical efficacy of treating ankylosing spondylitis(AS)with Qiangji decoction combined with western medicine therapy.Methods 60 AS patients were divided into the control group(n=30)and the treatment group(n=30)according to the random number table.Patients in the control group were treated with conventional western medicine therapy while the treatment group with Qiangji decoction based on the control group.There were two treatment cycles(45 days per cycle)for both groups.And then the treatment effects were evaluated.The scores of Bath Ankylosing Spondylitis Disease Activity Index(BASDAI),Bath Ankylosing Spondylitis Functional Index(BASFI),and pain Visual Analogue Scale(VAS)were compared in the two groups before and after treatment.And the duration of morning stiffness was also compared.Besides,changes in erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP)were compared in the two groups before and after treatment.And the adverse effects during the treatment were compared between the two groups.Results The total effective rate was 93.33%(28/30)in the treatment group while 73.33%(22/30)in the control group.And the adverse effects rate was 10.00%(3/30)in the treatment group while 33.33%(10/30)in the control group.So,the total effective rate in the treatment group was higher than that of the control group(P<0.05),while the adverse effects rate was lower(P<0.05).By comparison with the scores before treatment,the scores of BASDAI,BASFI,and pain VAS were obviously lower(P<0.05)and the duration of morning stiffness was obviously reduced(P<0.05)in the two groups after treatment.Moreover,each index score in the treatment group had an improvement and was higher than that of the control group after treatment(P<0.05).Besides,the post-treatment levels of ESR and CRP in the two groups were significantly lower than those results before treatment(P<0.05).And the post-treatment levels of ESR and CRP in the treatment group were lower than those of the control group.Conclusion It has a definite cur

关 键 词:脊柱炎 强直性 中西医结合疗法 

分 类 号:R289.61[医药卫生—方剂学] R593.23[医药卫生—中药学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象