14例新型冠状病毒肺炎患者的临床特点及重型患者的救治体会  

Analysis of the clinical characteristics of 14 patients with novel coronavirus pneumonia and treatment experience of severe patient

作　　者：宋惠雯 曾祥铨 连豫苞 李玉峰 SONG Huiwen;ZENG Xiangquan;LIAN Yubao;LI Yufeng(Sanming First Hospital of Fujian Medical University,Sanming,Fujian 365000,China)

机构地区：[1]福建医科大学附属三明第一医院,福建三明365000

出　　处：《现代医药卫生》2020年第23期3713-3716,3720,共5页Journal of Modern Medicine & Health

基　　金：福建省三明市科技局2020年第一批新冠肺炎防控技术研究项目(2020-S-3)。

摘　　要：目的分析福建省三明地区新型冠状病毒肺炎(COVID-19)的临床特征,为后续临床诊治提供参考。方法回顾性分析2020年1月25日至2020年3月5日该院收治的14例确诊为COVID-19患者的临床资料,探讨其临床特征。结果14例患者中男7例,女7例;平均年龄(39.0±11.9)岁;重型1例(7.1.%);出现咳嗽、乏力12例(85.7%),发热10例(71.4%),胸闷6例(42.9%),呼吸困难4例(28.6%),淋巴细胞计数低于10×10^9 L^-15例(35.7%),C反应蛋白升高7例(50.0%),红细胞沉降率升高10例(71.4%)。CT检查常见表现为双肺多发病灶,磨玻璃影,局部伴实变,多位于胸膜下。14例患者均接受了抗病毒治疗,应用抗生素12例(85.7%)。治愈率为100.0%,平均住院时间(23.1±8.7)d,治疗后核酸转阴时间4~32 d,平均(17.7±10.2)d。结论福建省三明地区COVID-19以青壮年多发,重型比例较低,疗效满意,诊治经验值得推广。Objective This study aimed to analyze the patients with novel coronavirus pneumonia(COVID-19)in Sanming,Fujian,and provide reference for clinical diagnosis and treatment.Methods The clinical data of 14 patients who diagnosed with COVID-19 from January 25 to March 5,2020 was analyzed retrospectively,and their clinical characteristics were explored.Results A total of 14 patients,among which 7 cases were male and 7 were female.The average age of them was(39.0±11.9)years,and 1(7.1%)patient was severe.12(85.7%)patients had cough and fatigue,10(71.4%)patients had fever,6(42.9%)patients had chest distress,and 4(28.6%)patients had dyspnea.The level of the lymphocyte count lower than 10×10^9 L^-1 was 5 patients(35.7%),the level of C-reactive protein increased was 7 patients(50.0%),and the erythrocyte sedimentation rate increased was 10 patients(71.4%).The computed tomography(CT)of the lungs showed that multiple ground glass shadow were mainly accompanied by consolidation,which often involved both lungs and located under the pleura.All the patients were treated with antiviral therapy,and 12(85.7%)patients took antibiotics.The cure rate of the patients was 100.0%,and the average in hospital time was(23.1±8.7)days.The shortest duration of negative conversion of virus was 4 days and the longest was 32 days,with an average of(17.7±10.2)days.Conclusion The novel coronavirus pneumonia is more frequent in young adults and has a relatively low proportion of severe type in Sanming.The treatment experience of COVID-19 in the Sanming First Hospital is worthy of popularizing,which had been achieving satisfactory results.

关 键 词：新型冠状病毒肺炎 流行病学 肺 体层摄影术 X线计算机 预后 回顾性研究 

分 类 号：R563.19[医药卫生—呼吸系统]