普通人群中外周血压与颅内动脉血流动力学参数关系的研究  

Relationship between blood pressure and hemodynamic parameters of intracranial arteries in general population

作　　者：陈雪涛 田锐[5] 李长彬 邢俊华 王海音 常俊霞 雷震 王新宴 CHEN Xuetao;TIAN Rui;LI Changbin;XING Junhua;WANG Haiyin;CHANG Junxia;LEI Zhen;WANG Xinyan(Department of Cardiology,Air Force Medical Center,Beijing 100142,China;不详)

机构地区：[1]空军特色医学中心神经内科,北京100142 [2]空军特色医学中心心内科,北京100142 [3]空军特色医学中心超声科,北京100142 [4]空军特色医学中心门诊部,北京100142 [5]空军航空大学门诊部,长春130000 [6]空军兰州招收飞行学员体检队,兰州730000

出　　处：《空军医学杂志》2020年第5期418-421,436,共5页Medical Journal of Air Force

基　　金：国家科技部基础性工作项目(2013FY114000);全军后勤科研重大项目(AKJ14R001)。

摘　　要：目的探讨普通人群中外周血压与颅内动脉血流动力学参数间的关系。方法选择2016年1—10月于空军特色医学中心进行门诊检查的150例志愿者,年龄19~85岁,平均(42.4±13.9)岁,男87例,女63例。记录志愿者一般资料:年龄、身高、体质量、体质量指数(BMI)和双侧上臂臂围(BC)。采用校正的汞柱血压计测量并记录志愿者双侧肱动脉收缩压和舒张压,每侧均测量3次取平均值记为右侧肱动脉收缩压(right brachial artery systolic blood pressure,RSBP)、肱动脉舒张压(right brachial artery diastolic blood pressure,RDBP)和左侧肱动脉收缩压(left brachial artery systolic blood pressure,LSBP)、肱动脉舒张压(left brachial artery diastolic blood pressure,LDBP),依据双侧肱动脉收缩压和舒张压将150例志愿者分为2组:血压正常组(74例)和血压增高组(76例)。采用CompanionⅢ经颅多普勒仪检测双侧大脑中动脉(middle cerebral artery,MCA)、颈内动脉终末段(internal carotid artery,ICA)、大脑前动脉(anterior cerebral artery,ACA)、大脑后动脉(posterior cerebral artery,PCA)、椎动脉(vertebral artery,VA)和基底动脉(base artery,BA)的收缩期峰值血流速度(Vs)、舒张末期血流速度(Vd)、平均血流速度(Vm)、搏动指数(pulsatility index,PI)和阻抗指数(resistant index,RI)的指标,分析血压与颅内动脉血流动力学参数间的关系。结果2组间年龄、体质量、BMI、RBC、RSBP、RDBP、LSBP、LDBP、RICA-PI、RICA-RI、LMCA-PI、LMCA-RI、LPCA-PI、LPCA-RI、RVA-Vd、RVA-Vm、LVA-PI、LVA-RI差异有统计学意义(P<0.05),均为血压增高组高于血压正常组;年龄与双侧MCA、ICA、ACA、VA和BA血管的Vs、Vd、Vm间呈负相关,特别在双侧MCA、ICA、VA和BA血管中相关性显著(P<0.01),与PI、RI呈正相关(P<0.05);身高与LACA、RVA、BA的Vs、Vd、Vm间呈负相关(P<0.05);体质量与LPCA、RVA、LVA、BA的Vs、Vd、Vm间呈负相关(P<0.05);BMI与LPCA、RVA、LVA、BA的Vs、Vd、Vm间呈负相关(PObjective To investigate the relationship between peripheral blood pressure and hemodynamic parameters of intracranial artery in general population.Methods From January to October 2016,150 volunteers,aged from 19 to 85 years old,with an average of(42.4±13.9)years old,were selected for outpatient examination in the Air Force Medical Center,including 87 males and 63 females.The general information of the volunteers was recorded:age,height,weight,body mass index(BMI)and bilateral biceps circumferenc(BC).The systolic and diastolic blood pressures of bilateral brachial arteries were measured and recorded with a calibrated mercury sphygmomanometer.The mean values were recorded as right brachial artery systolic blood pressure(RSBP),right brachial artery diastolic blood pressure(RDBP)and left brachial artery systolic blood pressure(LSBP),left brachial artery diastolic blood pressure(LDBP).According to the systolic and diastolic blood pressure of bilateral brachial arteries,150 volunteers were divided into two groups:normal blood pressure group(74 cases)and high blood pressure group(76 cases).The following index were measured by companionⅢtranscranial doppler instrument:middle cerebral artery(MCA)、internal carotid artery(ICA)、anterior cerebral artery(ACA)、posterior cerebral artery(PCA)、vertebral artery(VA)and base artery(BA),Systolic peak blood flow velocity(VS),end diastolic blood flow velocity(VD),mean blood flow velocity(VM),pulsatility index(PI)and resistant index(RI),The relationship between blood pressure and hemodynamic parameters of intracranial artery was analyzed.Results The differences in age,weight,BMI、RBC、RSBP、RDBP、LSBP、LDBP、RICAPI、RICA-RI、LMCA-PI、LMCA-RI、LPCA-PI、LPCA-RI、RVA-Vd、RVA-Vm、LVA-PI、LVA-RI between the two groups were statistically significant(P<0.05),All of them were higher in high blood pressure group than in normal blood pressure group;there was a negative correlation between age and Vs,Vd and Vm of bilateral MCA,ICA,ACA,VA and BA blood vessel.Especially in

关 键 词：肱动脉血压 脑血流速度 搏动指数 阻抗指数 

分 类 号：R544.1[医药卫生—心血管疾病]