经皮半月节球囊压迫术治疗三叉神经痛35例分析  

The effect and prognosis of 35 cases of trigeminal neuralgia treated by percutaneous semilunar ganglion balloon compression

作　　者：赵时雨[1] 刘星[1] 李国栋 熊文平[1] ZHAO Shiyu;LIU Xing;LI Guodong(Department of Neurosurgery,Zhongnan Hospital,Wuhan University,Wuhan 430071,China)

机构地区：[1]武汉大学中南医院神经外科,430071

出　　处：《临床外科杂志》2020年第10期920-923,共4页Journal of Clinical Surgery

摘　　要：目的分析经皮半月节球囊压迫术治疗三叉神经痛的效果。方法 2018年6月~2019年6月我院收治的三叉神经痛病人70例,按照随机数表法分为治疗组和对照组,每组各35例。对照组给予卡马西平治疗,持续用药1个月,治疗组给予经皮半月节球囊压迫术治疗。比较两组治疗1个月后临床疗效、视觉模拟评分法(VAS)变化、1年内复发率,并评价治疗安全性。结果治疗后1个月,治疗组疼痛缓解总有效率为97.14%,对照组为80.00%,两组比较差异有统计学意义(P<0.05);治疗组治疗后1周、2周、4周时的VAS评分均低于对照组(P<0.05);在两组治愈病人中,治疗组6个月、12个月时的复发率均低于对照组,且12个月复发时的VAS评分低于对照组,差异有统计学意义(P<0.05);治疗组术后主要并发症为术侧面部麻木、咀嚼肌无力、口角疱疹,对照组主要为眩晕、恶心呕吐、嗜睡。结论经皮半月节球囊压迫术治疗三叉神经痛疗效明显,可有效缓解疼痛症状,降低复发率,改善预后。Objective To studythe effect and prognosis of 35 cases of trigeminal neuralgia treated by percutaneous semilunar ganglion balloon compression.Methods 70 patients of trigeminal neuralgia who received therapy from June 2018 to June 2019 in our hospital were selected,they were divided into the treatment group and the control group by the random number table,35 cases in each group.The control group was treated with carbamazepine,continuous medication for 1 month,while the treatment group was treated with percutaneous transluminal balloon compression.The clinical effect,the change of visual analogue scale(VAS) and the recurrence rate within 1 year were compared between the two groups,and the safety of treatment was evaluated.Results After treatment of 1 month,the total effective rate of pain relief in the treatment group was 97.14%,which was significantly higher than that in the control group 80.00%(P<0.05);the VAS scores of the treatment group at after treatment 1,2 and 4 weeks were significantly lower than that in the control group(P<0.05);in the two groups of cured patients,the recurrence rate in the treatment group at 6 and 12 months was were significantly lower than that in the control group,and the VAS score at 12 months recurrence was significantly lower than that in the control group(P<0.05);the main complications of the treatment group were numbness of the operation side,weakness of masticatory muscles and herpes of the mouth,the main adverse reactions of the control group were dizziness,nausea,vomiting and drowsiness.Conclusion Percutaneous transluminal balloon compression is well for trigeminal neuralgia,which can effectively relieve the pain symptoms,reduce the recurrence rate and improve the prognosis.

关 键 词：三叉神经痛 经皮半月节球囊压迫术 卡马西平 复发率 安全性 

分 类 号：R651.1[医药卫生—外科学]