3D-Slicer软件在颅内病变手术定位中的应用  

Application of 3D-slicer software in preoperative localizationof intracranial lesions

作　　者：杨森源 周晓斌[1] 赖润龙[1] 陈煜[1] 薛泽彬 孙曼珊 李勇[1] YANG Senyuan;ZHOU Xiaobin;LAI Runlong(Department of Neurosurgery,the First Affiliated Hospital of Shantou University Medical College,Shantou 515041,China)

机构地区：[1]广东汕头大学医学院第一附属医院神经外科,515041 [2]广东汕头大学医学院护理系,515041

出　　处：《临床外科杂志》2020年第10期978-981,共4页Journal of Clinical Surgery

基　　金：广东省医学科学技术研究基金资助项目(A2018400)。

摘　　要：目的比较3D-Slicer软件与传统人工测量在神经外科术前定位的准确性。方法神经外科头颅病变(脑肿瘤,脑出血,外伤,异物,动脉瘤等)手术病人40例,利用个人电脑上3D-Slicer软件对病人头颅CT、MRI二维影像进行三维可视化影像重建,将重建的图像融合后导入到手机Sina软件中,利用虚拟现实(VR)眼镜在术中进行图像-头颅融合,对颅内病变进行体表定位,术前同时利用二维影像图像及体表标志进行传统人工测量的方法进行定位测量,比较两种方法优劣及准确性。结果40例病例中,采用3D-Slicer软件辅助术前定位方式,其最终定位距病变中心的距离为(0.24±0.14)cm,而采用传统定位方法的定位与病变中心距离为(0.48±0.30)cm,差异有统计学意义(P<0.05)。所有病例均未出现脑功能区及重要血管结构的损伤。结论相比于传统人工测量方法,3D-Slicer软件在神经外科术前定位中具有准确、快捷的特点。Objective To compare the accuracy of 3 D-Slicer software and traditional manual measuring method in preoperative localization of intracranial lesions.Methods 40 patients diagnosed with intracranial lesions(brain tumors,cerebral hemorrhage,traumatic brain injury,foreign bodies,aneurysm,etc).and met the inclusion criteria were selected in our research.The image data of the patients were collected and analyzed by 3 D-Slicer software on personal computers,resulting in visual data of three dimensional reconstruction.Then the data were imported into the mobile phone software"Sina".The data was generated and applied in preoperative localization by the virtual reality(VR)glasses.At the same time,the traditional manual measuring method with the help of two dimensionalimage data and markers were applied during surgery.Finally,the accuracy of the two methods were measured and analysed.Results Among the 40 cases,the preoperative localizations using the 3 D-Slicer software was closer to intracranial lesions,with a mean distance of(0.24±0.14)cm from the center of the intracranial lesion.On the other hand,using traditional manual measuring method,the preoperative localizations were with a mean distance of(0.48±0.30)cm from the center of the intracranial lesion,the difference between the two methods was statistically significant(P<0.05).There was no damage to brain functional areas or important vascular structures in all the cases.Conclusion Compared with the traditional manual measuring method,the localization using 3 D-Slicer software is more accurate and convenient in preoperativelocalization.

关 键 词：3D-Slicer软件 颅内病变 手术定位 

分 类 号：R651.1[医药卫生—外科学]