IVIM-DWI和DCE-MRI评估高强度聚焦超声刀治疗子宫肌瘤的疗效  

Comparison of IVIM-DWI and DCE-MRI in the treatment of uterine fibroids with high intensity focused ultrasound knife

作　　者：鲁辛健 班允清[1] 王晓燕[1] 丁晓燕 LU Xinjian;BAN Yunqing;WANG Xiaoyan;DING Xiaoyan(CT MRI Room,The Fifth Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,China)

机构地区：[1]新疆医科大学第五附属医院CT核磁室,新疆乌鲁木齐830011

出　　处：《分子影像学杂志》2020年第4期557-562,共6页Journal of Molecular Imaging

基　　金：新疆维吾尔自治区自然科学基金(2018D01C298)。

摘　　要：目的分析体素内不相干运动扩散加权成像(IVIM-DWI)和动态对比增强MRI(DCE-MRI)定量参数对高强度聚焦超声刀治疗子宫肌瘤疗效的比较。方法对60例子宫肌瘤患者进行高强度聚焦超声消融术,所有患者在术前1周、术后48 h及术后3月分别行IVIM-DWI及DCE-MRI检查,通过相关参数(ADC、eADC、StandardADC、f值、D值、D*值、MSI、SER)对同一肌瘤比较IVIM-DWI与DCE-MRI在消融和未消融区域的差异,分析两种扫描参数之间是否具有相关性。结果术后48 h、术后3月的DCE-MRI相关参数MSI、SER与IVIM-DWI相关参数D*与f值与术前差异具有统计学意义(P<0.05),IVIM-DWI相关参数f与D*值与DCE-MRI相关参数MSI、SER有显著正相关性。结论IVIM-DWI所产生的伪彩图相较DCE-MRI对子宫肌瘤消融界限较难以区分,但IVIM-DWI相关参数仍能对子宫肌瘤HIFU术后早期病灶的血供及灌注情况提供一定的参考价值。Objective To compare the efficacy of IVIM-DWI and DCE-MRI in the treatment of uterine fibroids with highintensity focused ultrasound scalpel.Methods 60 patients with hysteromyoma underwent high intensity focused ultrasound ablation.IVIM-DWI and DCE-MRI were performed in all patients 1 week before operation,48 hours after operation and 3 months after operation respectively.The differences between IVIM-DWI and DCE-MRI in ablated and UN ablated areas were compared between IVIM-DWI and DCE-MRI through relevant parameters(ADC,eADC,standardABC,f value,D value,D*value,MSI,SER).The correlation between the two scanning parameters was analyzed.Results The values of D*and F related with IVIM-DWI and the MSI,SER value of DCE-MRI at 48 h and 3 months after operation were significantly different from those before operation(P<0.05).And there was a significant positive correlation between the values of F and D*of IVIMDWI and MSI and SER of DCE-MRI.Conclusion Compared with DCE-MRI,IVIM-DWI can not distinguish the ablation boundary of hysterical,but the parameters of IVIM-DWI can still provide some reference value for the blood supply and perfusion of uterine leiomyoma in the early stage after HIFU.

关 键 词：子宫肌瘤 高强度聚焦超声 DCE-MRI IVIM-DWI 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.33[医药卫生—诊断学]