COVID-19在不同时期的胸部CT表现及出院后核酸复阳肺内病灶变化特点  

Chest CT findings of COVID-19 in different stages and the changes in lung lesions with positive for nucleic acid test after discharge

作　　者：林红东 蓝博文 周玉祥 马伟琼 陈镜聪 LIN Hongdong;LAN Bowen;ZHOU Yuxiang;MA Weiqiong;CHEN Jingcong(Department of Radiology,Huizhou Central People's Hospital,Huizhou 516001,China)

机构地区：[1]惠州巿中心人民医院放射科,广东惠州516001

出　　处：《分子影像学杂志》2020年第4期705-708,共4页Journal of Molecular Imaging

摘　　要：目的探讨COVID-19在不同时期的胸部CT表现及出院后核酸复阳肺内病灶变化特点。方法回顾性分析54例COVID-19患者的临床资料及影像学表现,通过3次以上胸部CT检查动态观察病灶变化,对比住院期间及出院后核酸检测复阳患者的胸部CT改变。结果78%的病例近14 d去过武汉市或湖北省,22%的病例无去武汉市或湖北省史;普通型51例(94%),重型3例(6%);单叶单灶2例(3.7%),单叶多灶3例(5.6%),多叶多灶例49例(90.7%);沿胸膜下分布为主46例,沿血管束分布为主6例,沿肺叶分布2例;磨玻璃(GGO)54例,GGO伴局灶实变28例,GGO伴细网格征34例,GGO伴晕征23例,含气囊腔征3例,蜂窝征1例;血管束增粗14例,支气管增粗或扩张18例;1例伴双侧少量胸腔积液。早期表现单发或多发斑片磨玻璃灶;进展期病灶数量增多、范围增大、密度增高、局部实变或大片实变;重症期双肺多发或弥漫磨玻璃密度背景下节段或肺叶实变;转归期病灶缩小、密度不均匀减低,大部分病灶完全消失,少量形成纤维条索;6例(11.5%)在转归期出现“此消彼长”表现。47例(87%)在7~14 d病灶开始吸收,7例(13%)病灶开始吸收时间在14 d后。46例符合临床出院标准时,出院前胸部CT仍见多发磨玻璃病灶;9例出院后7~15 d出现核酸检测复阳,2例核酸复阳出现在15 d后,但其肺内病灶较上一次CT(出院前)吸收减少,未见新增病灶。结论COVID-19不同时期影像学表现不同,其转归过程有一定的特征及规律,正确认识及掌握其影像学变化对其早期诊断、排查及疗效评估有重要价值。Objective To investigate the absorptive characteristics and the CT imaging features of COVID-19 in different stages and the changes in lung lesions with positive for nucleic acid test after discharge.Methods The CT imaging and clinical manifestations of 54 patients with COVID-19 were restrospectively analyzed.Through more than 3 times of chest CT examination to dynamically observe the changes of lesions,the changes of chest CT in patients with positive of nucleic acid test after discharge were compared with the last chest CT examination during hospitalization.Results 42 patients(78%)come from Wuhan or Hubei to Huizhou in recent 14 days and 22%of the cases had no history of going to Wuhan or Hubei Province.Among them,51 common type case(94%),3 critical type case(6%)were divided by clinical symptoms and CT findings.Single lesion was located in the single pulmonary lobe in 2 cases;multiple lesions were located in the single pulmonary lobe in 3 cases;multiple lesions were located in the multiple pulmonary lobe in 49 cases;most lesions were located on the subpleural area in 46 cases;6 cases were extended along the bronchovascular bundle;2 cases were distributed along the pulmonary lobe.Ground glass opacities(GGO)were found in 54 patients;Consolidation was found in 28 cases;Interlobular septal thickening was appeared in GGO in 34 cases;Halo sign with GGO was found in 23 cases;Air sacs was occurred in the lesions of GGO or consolidation in 3 cases,and honeycomb sign was appeared in 1 case.Vascular bundle thickening in 14 cases,Bronchial thickening or dilatation in 18 cases,bilateral small amount of pleural effusion in 1 case.In early stage,patchy GGO was found on the subpleural area in 54 patients.In advanced stage,the number,density and range of lesions were more,denser and larger than those in the early stage.Segment or lobe consolidation in the background of diffuse or multiple ground glass opacities with double lungs in critical stage.In absorption stage,the lesions were significantly smaller and lighter in density,

关 键 词：COVID-19 不同时期 胸部CT表现 转归 出院后 核酸复阳 

分 类 号：R563.1[医药卫生—呼吸系统]