阴道超声测量子宫内膜厚度、阻力指数结合β-HCG检测与异位妊娠患者临床症状的关系  

Relationship between vaginal ultrasound measurement of ET and RI combined withβ-HCG and clinical symptoms of EP patients

作　　者：李美娜 潘慧君 卞敏[1] 李琴[1] LI Meina;PAN Huijun;BIAN Min;LI Qin(Department of Ultrasound,Jiangsu Taizhou People's Hospital,Taizhou 225300,China)

机构地区：[1]泰州市人民医院超声科,江苏泰州225300

出　　处：《分子影像学杂志》2020年第4期717-720,共4页Journal of Molecular Imaging

摘　　要：目的分析阴道超声测量子宫内膜厚度(ET)、血流阻力指数(RI)与β-HCG检测与异位妊娠(EP)患者临床症状的关系及其在EP鉴别诊断中的应用价值。方法选择2017年1月~2019年3月间收治的60例符合EP患者作为EP组,50例人工中止妊娠及50例自然流产孕妇作为人工中止妊娠组及自然流产组;采用阴道超声测量ET、RI水平,并检测患者血中β-HCG水平;绘制ROC曲线分析ET、RI与β-HCG联合检测在鉴别诊断EP患者中的应用价值,采用logistics多元回归模型分析各指标与EP患者临床症状关系。结果EP组、自然流产组及人工中止妊娠组患者ET、RI及β-HCG水平差异有统计学意义(P<0.05),其中EP组患者ET及β-HCG水平最低,RI最高;ET、RI及β-HCG是影响EP患者临床症状的独立性影响因素(P<0.05);ET、RI、β-HCG联合应用鉴别诊断在EP中的敏感度、特异度及AUC均明显高于各指标单独应用(P<0.05)。结论阴道超声测量ET、RI及血中β-HCG水平是影响EP患者临床症状的独立影响因素,且各指标联合应用可有效提高单独应用的临床应用价值。Objective To explore the relationship between vaginal ultrasound measurement of ET,RI andβ-HCG and clinical symptoms of patients with EP and its application value in the differential diagnosis of EP.Methods Sixty patients with EP who were admitted between January 2017 and March 2019 were selected as the EP group,50 pregnant women with artificial abortion and 50 pregnant women with spontaneous abortion were selected as the artificial abortion group and spontaneous abortion group;vaginal ultrasound was used to measure ET and RI Level,and detect theβ-HCG level in patients'blood;ROC curve was used to analyze the application value of combined detection of ET,RI andβ-HCG in differential diagnosis of EP.Logistic multiple regression model was used to analyze the relationship between each index and clinical symptoms of EP patients.Results There were significant differences in the levels of ET,RI andβ-HCG in the EP group,spontaneous abortion group and artificial abortion group,and the differences were statistically significant(P<0.05).Among the patients in the EP group,ET andβ-HCG levels were the lowest,and RI was the highest.ET,RI andβ-HCG are independent factors influencing the clinical symptoms of EP patients,which are statistically significant(P<0.05).The sensitivity,specificity,and AUC of differential diagnosis in EP combined with ET,RI,andβ-HCG are obviously higher than each index alone,and the difference was statistically significant(P<0.05).Conclusion Vaginal ultrasound measurement of ET,RI,and bloodβ-HCG levels are independent factors affecting the clinical symptoms of EP patients,and the combined application of each index can effectively increase the value of clinical application of single application.

关 键 词：阴道超声 子宫内膜厚度 阻力指数 Β-HCG 异位妊娠 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.22[医药卫生—诊断学]