腹腔镜下输卵管线性切开术与输卵管妊娠部位切除后端端吻合术治疗输卵管妊娠的对照分析  

Comparison of Laparoscopic Linear Salpingotomy and Tubal Pregnancy Site Resection with End-to-end Anastomosis in the Treatment of Tubal Pregnancy

作　　者：陈少芬 陈秀芬 卫凤英 CHEN Shaofen;CHEN Xiufen;WEI Fengying(Shunde Women’s Hospital of Guangdong Medical University(Foshan Shunde District Maternal and Child Health Hospital),Foshan 528300,China;不详)

机构地区：[1]广东医科大学顺德妇女儿童医院(广东省佛山市顺德区妇幼保健院),广东佛山528300

出　　处：《中国医学创新》2020年第35期116-120,共5页Medical Innovation of China

基　　金：佛山市卫生和计生局医学科研课题(20180303)。

摘　　要：目的:对比腹腔镜下输卵管线性切开术与输卵管妊娠部位切除后端端吻合术治疗输卵管妊娠的效果。方法:选取2018年1月-2020年6月本院收治的输卵管妊娠患者14例作为研究对象,采用随机数字法分为试验组和对照组,每组7例。对照组行腹腔镜下输卵管线性切开术,试验组则采用输卵管妊娠部位切除后端端吻合术。比较两组患者术后输卵管通畅情况及血β-hCG恢复正常时间,并于术后1周、1个月及3个月测定和比较两组的血P、FSH、T、LH、E2和AMH水平。结果:两组术后输卵管通畅率比较,差异无统计学意义(P>0.05)。试验组血β-hCG恢复正常时间短于对照组,差异有统计学意义(P<0.05)。术后1周、1个月和3个月,试验组的血P、T、AMH水平均高于对照组,FSH均低于对照组,差异均有统计学意义(P<0.05);两组的LH和E2水平比较,差异均无统计学意义(P>0.05)。结论:对输卵管妊娠患者实施腹腔镜下输卵管线性切开术与输卵管妊娠部位切除后端端吻合术的输卵管通畅率均较高,但后者在保留输卵管的同时对患者卵巢储备功能影响更小。Objective:To compare the effect of laparoscopic linear salpingotomy and tubal pregnancy site resection with end-to-end anastomosis in the treatment of tubal pregnancy.Method:A total of 14 patients with tubal pregnancy admitted to our hospital from January 2018 to June 2020 were enrolled.The patients were divided into experimental group and control group by digital randomization method,7 cases in each group.Patients in the control group were treated with laparoscopic linear salpingotomy,while those in the experimental group were treated with tubal pregnancy site resection and end-to-end anastomosis.The tubal patency and bloodβ-hCG recovery time of the two groups were compared,and blood P,FSH,T,LH,E2 and AMH levels were measured and compared at 1 week,1 month and 3 months after surgery between the two groups.Result:There was no statistically significant difference in the rate of fallopian tube recanalization between the two groups(P>0.05).The recovery time ofβ-hCG in experimental group was shorter than that in control group,the difference was statistically significant(P<0.05).At 1 week,1 month and 3 months after surgery,the blood levels of P,T and AMH in the experimental group were all higher than those in the control group,and FSH were lower than those in the control group,with statistically significant differences(P<0.05);there were no significant differences in LH and E2 levels between the two groups(P>0.05).Conclusion:The rate of fallopian tube patency after laparoscopic linear salpingectomy and tubal pregnancy site resection and end-to-end anastomosis are higher in the patients with tubal pregnancy,however,the latter had less effect on ovarian reserve function while preserving fallopian tubes.

关 键 词：输卵管妊娠 输卵管线性切开术 妊娠部位切除后端端吻合术 卵巢功能 

分 类 号：R713.8[医药卫生—妇产科学]