重型颅脑损伤患者呼吸机相关性肺炎对脑功能恢复的意义  

Significance of Ventilator-associated Pneumonia on the Recovery of Brain Function in Patients with Severe Head Injury

作　　者：张芸[1] 祁恒旭[2] 付文良[1] 臧仕国 ZHANG Yun;QI Hengxu;FU Wenliang;ZANG Shiguo(Department of Emergency ICU,Dalian Central Hospital,Dalian 116000,China;Department of Neurology,Dalian Central Hospital,Dalian 116000,China)

机构地区：[1]大连市中心医院急诊ICU,辽宁大连116000 [2]大连市中心医院神经内科,辽宁大连116000

出　　处：《中国医药指南》2020年第31期84-85,共2页Guide of China Medicine

摘　　要：目的探讨重型颅脑损伤患者呼吸机相关性肺炎对脑功能恢复的意义。方法选取2018年1月至2019年1月于大连市中心医院急诊ICU及神经内科就诊的75例重型颅脑损伤患者,按照其是否合并呼吸机相关肺炎分为试验组(40例,合并呼吸机相关肺炎)和对照组(35例,未合并呼吸机相关肺炎),比较两组患者出院后脑功能恢复情况和神经功能恢复情况。结果治疗前,两组脑功能障碍评分(DRS)比较,差异无统计学意义(P>0.05);治疗后,试验组DRS评分高于对照组,差异有统计学意义(P<0.05)。治疗后,试验组、胶质纤维酸性蛋白、胶质纤维酸性蛋白优于对照组,差异均有统计学意义(P<0.05)。结论呼吸机相关性肺炎会对重型颅脑损伤患者的脑功能的恢复产生影响,临床应尽量避免呼吸机相关性肺炎的发生。Objective To investigate the significance of ventilator-associated pneumonia in the recovery of brain function in patients with severe craniocerebral trauma.Methods Select 75 patients with severe head injury who attended the Department of Emergency ICU and Neurology,Dalian Central Hospital from January 2018 to January 2019,and divided them into the experimental group according to whether they were combined with ventilator-related pneumonia(40 cases,combined with ventilator-related pneumonia)and the control group(35 cases,without ventilator-associated pneumonia).The recovery of brain function and nerve function after discharge from the two groups were compared.Results Before treatment,there was no significant difference between the two groups of brain dysfunction score(DRS)(P>0.05);after treatment,the DRS score of the test group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the test group,glial fibrillary acidic protein,and glial fibrillary acidic protein were better than the control group,and the differences were statistically significant(P<0.05).Conclusion Ventilator-associated pneumonia in patients with severe craniocerebral trauma is important for the recovery of brain function,and ventilator-associated pneumonia should be avoided as far as possible.

关 键 词：重型颅脑损伤 呼吸机相关性肺炎 脑功能 神经功能 

分 类 号：R651.15[医药卫生—外科学]