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作 者:甄文博 ZHEN Wenbo(Peixian Hospital of Traditional Chinese Medicine,Xuzhou 221600,China)
机构地区:[1]沛县中医院,江苏徐州221600
出 处:《中国医药指南》2020年第31期130-132,共3页Guide of China Medicine
摘 要:目的探讨喜炎平注射液辅助治疗细菌性肺炎患儿的效果。方法选择2018年12月至2019年12月沛县中医院收治的60例细菌性肺炎患儿作为研究对象,根据治疗方法的不同分为对照组(30例,采用常规抗感染药物治疗)和观察组(30例,在对照组基础上联合喜炎平注射液治疗),比较两组患儿治疗前后的血清炎性因子水平、临床症状改善时间以及并发症发生情况。结果治疗前,两组患儿的IL-6、CRP、TNF-α水平比较,差异均无统计学意义(P>0.05);治疗3 d后,观察组IL-6、CRP、TNF-α水平的改善效果明显优于对照组,差异均有统计学意义(P<0.05);观察组患者发热消失时间、咳嗽症状消失时间、肺啰音消失时间、住院时间均短于对照组,差异均有统计学意义(P<0.05);观察组并发症发生率明显低于对照组,差异有统计学意义(P<0.05)。结论针对细菌性肺炎患儿,应用常规抗感染药物能达到一定效果,但联合喜炎平注射液治疗可使患儿的炎症控制效果更佳,有助于尽快改善患儿的临床症状。Objective To investigate the effect of xiyanping injection in the adjuvant treatment of children with bacterial pneumonia.Methods From December 2018 to December 2019,60 cases of children with bacterial pneumonia in our hospital were selected as the research object,and they were divided into control group(30 cases,treated with conventional anti infective drugs)and observation group(30 cases,treated with xiyanping injection on the basis of the control group).The levels of serum inflammatory factors and clinical symptoms of the two groups were observed before and after treatment improvement time and incidence of complications.Results Before treatment,there was no significant difference in the levels of IL-6,CRP and TNF-αbetween the two groups(P>0.05).After 3 days of treatment,the improvement effect of IL-6,CRP,TNF-αlevels in the observation group was significantly better than that in the control group,the differences were statistically significant(P<0.05).The disappearance time of fever,cough symptoms,pulmonary rales and hospitalization time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).The incidence of complications in the observation group was significantly lower than that in the control group,and the differences were statistically significant(P<0.05).Conclusion For children with bacterial pneumonia,the application of conventional anti infective drugs can achieve a certain effect,but combined with xiyanping injection treatment,children's inflammation control effect is better,can improve the clinical symptoms of children as soon as possible,worthy of clinical application.
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