成人肝移植术后早期肝动脉血栓形成的非手术因素  

Early hepatic artery thrombosis after liver transplantation in adults:a review of nonsurgical factors

作　　者：鲍邦和 张帆[1] 木塔力甫·斯莱曼 王文静 陈庆[1] Bao Banghe;Zhang Fang;Mutalifu Silaiman;Wang Wenjing;Chen Qing(Department of Hepatobiliary Surgery,Union Hospital of Tongji Medical College,Huazhong University of Science and Technology,Hubei Wuhan 430022,China;Department of Pediatric Surgery,Tongji Hospital of Tongji Medical College,Huazhong University of Science and Technology,Hubei Wuhan 430030,China)

机构地区：[1]华中科技大学同济医学院附属协和医院肝胆外科,湖北武汉430022 [2]华中科技大学同济医学院附属同济医院小儿外科,湖北武汉430030

出　　处：《腹部外科》2020年第6期474-477,F0003,共5页Journal of Abdominal Surgery

摘　　要：肝动脉血栓(hepatic artery thrombosis,HAT)是肝移植术后最常见的一种血管并发症,是导致移植物功能丧失的主要原因之一。已知多个危险因素可导致HAT的发生,其中动脉吻合技术与早期血栓的形成密切相关,但这一问题随着显微外科技术的进步得到缓解;除了技术原因,其他的危险因素包括低供者/受者体重比、感染、免疫、凝血异常和吸烟等,特别是供、受者吸烟史最近被认为是早期HAT的危险因素。该文对这些危险因素进行了综述,其中重点讨论吸烟对移植术后HAT产生的影响。Hepatic artery thrombosis(HAT)is the most common vascular complication,and also one of the principal causes of graft loss following liver transplantation.There are several risk factors for the development of HAT.Technical aspects of arterial anastomosis are important particularly for early HAT,but with the development of microsurgery technique,this problem has been lessened.Apart from technical causes,other risk factors include low donor/recipient weight ratio,infection,immunologic factors,coagulation abnormalities,and smoking,etc.Especially the history of smoking of donor and recipient has recently been considered as risk factors for early HAT.This review evaluates these aspects,focusing on the impact of smoking on HAT after transplantation.

关 键 词：肝移植 肝动脉血栓 并发症 危险因素 吸烟 

分 类 号：R619.2[医药卫生—外科学]