气相色谱法测定工作场所空气中芳香族硝基化合物的方法改进  

Improvement of determination method for nitroaromatic compounds in the air of workplace by gas chromatography

作　　者：刘亚攀 王敏 杨莉 江金凤 LIU Ya-pan;WANG Min;YANG Li;JIANG Jin-feng(Wwhan Prevention and Treatment Center for Occupatioral Diseases,Wuhan,Hubei 430015,China)

机构地区：[1]武汉市职业病防治院卫生检验科,湖北430015

出　　处：《现代预防医学》2020年第23期4260-4263,4330,共5页Modern Preventive Medicine

基　　金：湖北省重点实验室开放基金项目(OHIC2018G07)。

摘　　要：目的改进工作场所空气中芳香族硝基化合物的气相色谱测定方法。方法硅胶管和超细玻璃纤维滤纸采集的芳香族硝基化合物,分别用丙酮和5%乙醇-正己烷解吸和洗脱,DB-17MS毛细管色谱柱分离,电子捕获检测器检测,外标法定量。结果 9种芳香族硝基化合物均在9.5 min内出峰,分离良好,平均解吸或洗脱效率为93.6%~100.9%,检出限范围0.0015~2.5μg/ml,相对标准偏差0.5%~3.6%。结论改进后的方法精密度和准确度高,适用于工作场所空气中芳香族硝基化合物的测定。Objective To improve the determination method of nitroaromatic compounds in workplace air by gas chromatography.Methods The target analytes were collected by silica gal sampling tubes or glass fiber filters,desorbed with acetone or eluted with 5%ethanol-n-hexane,separated by DB-17 MS capillary column,detected by electron capture detector,and quantified by external standard method.Results The 9 nitroaromatic compounds were well separated within 9.5 min.The average desorption or elution efficiencies were 93.6%-100.9%.The detection limits were 0.0015-2.5μg/ml.The relative standard deviations were 0.5%-3.6%.Conclusion The improved method is accurate,reliable and can be applied to the determination of nitroaromatic compounds in workplace air.

关 键 词：工作场所空气 芳香族硝基化合物 气相色谱法 

分 类 号：R122.1[医药卫生—环境卫生学]