稻丰散合成工艺路线改进研究  

Study on Improvement of Synthetic Technology of Phenthoate

作　　者：程晓兵 王玉 徐兵 Cheng Xiaobing;Wang Yu;Xu Bing(Jiangsu Tenglong Biological Pharmaceutical Co.,Ltd.,Yancheng 224145,China;Yancheng Suhai Pharmaceutical Co.,Ltd.,Research and Development Center,Yancheng 224125,China)

机构地区：[1]江苏腾龙生物药业有限公司,江苏盐城224145 [2]盐城苏海制药有限公司研发中心,江苏盐城224125

出　　处：《山东化工》2020年第22期46-47,52,共3页Shandong Chemical Industry

摘　　要：稻丰散是一种中等毒性的有机磷杀虫剂,为降低生产成本和原料消耗对稻丰散的合成路线进行工艺改进。本文选用三氯氧磷作为催化剂合成ɑ-溴代苯乙酸作为关键合成工艺路线,使原料溴素的吨消耗从1000 t下降至700 t,稻丰散原油的含量达95%,收率达94%以上,大大降低原材料的消耗,节约了生产成本,提高了稻丰散在有机磷农药的市场中的竞争力。Phenthoate is a moderately toxic organophosphate insecticide.In order to reduce the production cost and raw material consumption,the synthetic route of Phenthoate was improved.This article selects the phosphorus oxychloride as catalyst for synthesis ofɑ-bromine generation of phenylacetic acid as the key synthesis process route,the raw bromide tons consumption decreased from 1000 tons to 700 tons,rice feng scattered oil content was 95%,and the yield of above 94%,and significantly reduce the consumption of raw materials,saves the production cost,improve the rice feng in organophosphorus pesticides in the market competitiveness.

关 键 词：稻丰散 三氯氧磷 溴素 

分 类 号：TQ456.1[化学工程—农药化工] R978.1[医药卫生—药品]