肠道菌群与子宫内膜癌关系研究进展  

Advancement in relationship between intestinal microflora and endometrial cancer

作　　者：谢玉培 勒孚银 谭布珍(指导)[1] XIE Yu-Pei;LE Fu-Yin;TAN Bu-Zhen(Second Affiliated Hospital of Nanchang University,Nanchang 330006,China)

机构地区：[1]南昌大学第二附属医院,南昌330006

出　　处：《中国免疫学杂志》2020年第22期2815-2816,F0003,I0002,共4页Chinese Journal of Immunology

摘　　要：子宫内膜癌是女性常见的恶性肿瘤之一,其发病率介于宫颈癌与卵巢癌之间,病因尚不明确,发病危险因素多样,与多种良性疾病如胰岛素抵抗、肥胖等相关。肠道微生物是人体数量最大的“共生菌”,其数量多达人体细胞总数的10倍。近年来,肠道微生物的研究取得了巨大进展,不仅全面揭示了肠道微生物的生理学功能,还进一步阐明了其与良性疾病和恶性肿瘤的关系。本文就肠道微生物对子宫内膜癌发生、治疗、预后的影响进行讨论与总结,并初步探讨肠道微生物在子宫内膜癌预防、治疗、预后中的应用。Endometrial cancer is one of the common malignant tumors in women,which incidence rate is between cervical cancer and ovarian cancer.The etiology is still unknown and the risk factors are various.It is related to various benign diseases such as insulin resistance and obesity,et al.Intestinal microbes are the largest number of"symbiotic bacteria"in human body,and their number is even 10 times of the total number of human cells.In recent years,great progress has been made in study of intestinal microbes,which not only fully reveals physiological functions of intestinal microbes but also further clarifies its relationship with benign diseases and malignant tumors.In this paper,effects of intestinal microbes on the occurrence,treatment and prognosis of endometrial cancer were discussed,and application of intestinal microbes in prevention,treatment and prognosis of endometrial cancer were discussed.

关 键 词：肠道微生物 子宫内膜癌 胰岛素抵抗 肥胖 

分 类 号：R711.75[医药卫生—妇产科学]