老年综合征与老年人睡眠障碍的相关性分析  

Correlation analysis between geriatric syndrome and sleep disorder in the elderly

作　　者：赵翠[1] 霍静 王淼[1] 王兆鹏[1] 王玉玲 王义围[1] 郭艳娥 Zhao Cui;Huo Jing;Wang Miao;Wang Zhaopeng;Wang Yuling;Wang Yiwei;Guo Yan’e(Department of General Medicine,Affiliated Hospital of Chengde Medical College,Chengde 067000,China;Department of Neurology,the Third Hospital of Hebei Medical Utuversity,Shijiazhuang 067000,China;The Second Medical Center of General Hospital of the Chinese People’s Liberation Army,Beijing 100040,China)

机构地区：[1]承德医学院附属医院全科医疗科,067000 [2]河北医科大学第三医院神经内科,石家庄067000 [3]中国人民解放军总医院第二医学中心,北京100040

出　　处：《中华老年医学杂志》2020年第12期1430-1433,共4页Chinese Journal of Geriatrics

基　　金：2018年度河北省医学科学研究重点课题计划(20181156)。

摘　　要：目的观察老年综合征患者睡眠结构和睡眠障碍的临床特征,分析睡眠障碍与老年综合征的相关性。方法横断面研究,根据老年综合评估结果入选我院年龄≥60岁老年综合征患者200例(综合征组),年龄(73.5±4.1)岁,选取同期在我院行体检的健康老年人200例为对照组,年龄、性别与综合征组患者相匹配。观察两组匹茨堡睡眠质量指数量表(PSQI)评分和多导睡眠监测(PSG)指标。结果综合征组患者的空腹血糖高于对照组(P<0.05),PSQI评分亦高于对照组[(7.8±1.7)分比(6.3±1.2)分,P<0.01]。老年综合征患者PSQI总分与老年综合征的数量呈正相关(r= 0.95,P<0.01)。老年综合征组和对照组睡眠S1阶段、总记录时间比较差异无统计学意义(均P>0.05);综合征组快动眼睡眠(REM)时间、睡眠效率、慢波睡眠、睡眠潜伏期低于对照组(均P<0.05);REM密度、REM强度、睡眠时间、醒觉次数、醒觉时间、S2阶段、REM活动度高于对照组(P<0.05)。PSG检测结果显示,综合征组和对照组总记录时间、S1阶段比较差异无统计学意义(均P>0.05);综合征组睡眠时间、睡眠效率、慢波睡眠、快速眼动相睡眠潜伏期、REM睡眠时间低于对照组(P<0.05)。结论老年患者的睡眠质量随老年综合征数量增多而变得更差;PSG监测手段有助于早期发现并识别合并老年综合征患者的失眠问题。Objective To observe clinical features of sleep structure and sleep disorder in elderly patients with geriatric syndrome,and to analyze the correlation between sleep disorder and geriatric syndrome.Methods This was a cross-sectional study.Patients aged≥60 ycars(73.5±4.1 years)diagnosed as geriatric syndrome were enrolled as a geriatric syndrome group(n=200).The age-and gender-matched elderly subjects being healthy confirmed by regular health checking in our hospital during the same period were enrolled as a control group(n=200).The Pittsburgh Sleep Qualit Index(PSQI)scores and polysomnography(PSG)indexes were observed in the two groups.Results The fasting blood glucose level was higher in the geriatric syndrome group than in the control group(P<0.05).The PSQI score was higher in the geriatric syndrome group than in the control group(7.8±1.7 vs.6.3i 1.2,P<0.01).The total score of PSQI was positively correlated with number of elderly syndrome components in the geriatric syndrome group(r=0.95,P<0.01).There was no significant difference in sleep stage S1 and total recording time between the two groups(P>0.05).The rapid eye movement sleep(REM)time,sleep efficiency,slow wave sleep,sleep latency were lower,while the REM intensity,REM density,sleeping time,awakening numbers,awakening time,sleep stage S2 and REM activity were higher in the geriatric syndrome group than in the control group(P<0.05).PSG test results showed that there was no statistical difference in total recording time and sleep stage S1 between the two groups(P>0.05).The sleep time,sleep efficiency,slow wave sleep(SWS),REM sleep latency and REM sleep time were lower the geriatric syndrome group than in the control group(P<0.05).Conclusions The sleep quality is worse along with the increase of the number of geriatric syndromes components in elderly patients.PSG monitoring technology is helpful for early detection and identification of insomnia in patients with geriatric syndrome.

关 键 词：老年综合征 睡眠障碍 多道睡眠描记术 

分 类 号：R592[医药卫生—老年医学] R740[医药卫生—内科学]