氯己定过敏研究现状  

Status of research on chlorhexidine allergy

作　　者：肖浩[1] 张虹婷[1] 张莉[1] 贾巧茹 孟娟[1] XIAO Hao;ZHANG Hong-ting;ZHANG Li;JIA Qiao-ru;MENG Juan(Allergy Center of Otolaryngology,Head and Neck Surgery Department,West China Hospital,Sichuan University,Chengdu 610041)

机构地区：[1]四川大学华西医院耳鼻咽喉头颈外科过敏性疾病诊治中心,成都610041

出　　处：《中华临床免疫和变态反应杂志》2020年第5期465-470,共6页Chinese Journal of Allergy & Clinical Immunology

基　　金：四川大学华西医院学科卓越发展1·3·5工程临床研究孵化项目(2018HXFH026)。

摘　　要：氯己定是一种广谱杀菌剂、消毒剂,在医疗及相关产品中应用非常广泛。尽管氯己定诱发过敏反应并不常见,但可能由于使用频率增加,过敏反应的发生率呈上升趋势。由于对氯己定的致敏性认知不足且暴露隐匿,极易造成漏诊。本文对氯己定过敏的现状、潜在暴露途径、临床表现、易被漏诊原因、诊断方法、预防措施、临床及相关应用的必要性及存在的问题等进行综述,以期提高广大医务工作者对氯己定过敏的认识。Chlorhexidine is one kind of broad-spectrum antiseptics and disinfectants,which is widely used in medical and related products.Although allergic reactions caused by chlorhexidine are not common,its incidence may be on the rise due to increasing frequency of application.Missed diagnosis of chlorhexidine allergy is extremely common,because of lack of knowledge on allergenicity of chlorhexidine and its recessive exposure.Current data of epidemiology,potential exposure routes,clinical manifestations,reasons for missed diagnosis,diagnostic methods,preventive measures,necessity of application and existing problems of chlorhexidine allergy were reviewed in this article,aimed to improve the awareness of medical workers for chlorhexidine allergy.

关 键 词：氯己定 皮肤消毒剂 尿道凝胶 中央静脉导管 围手术期 

分 类 号：R59[医药卫生—内科学]