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作 者:吴波 陈文文 梁华 张丹 谭婕 李根 WU Bo;CHEN Wenwen;LIANG Hua;ZHANG Dan;TAN Jie;LI Gen(Department of Pharmacy,Chengdu Women's and Childrn's Central Hosptal,School of Medcie,Ulnioerity of Elecronic Srience and Techmology of China,Chengdu,Sichuan,China 610073)
机构地区:[1]电子科技大学医学院附属妇女儿童医院·成都市妇女儿童中心医院药学部,四川成都610073
出 处:《中国药业》2020年第24期48-51,共4页China Pharmaceuticals
基 金:四川省卫生和计划生育委员会科研课题[17PJ573]。
摘 要:目的为优化自然临产经阴道分娩临床路径用药及开展临床药学监护提供参考。方法回顾性分析医院2017年1月至2018年6月进入自然临产经阴道分娩临床路径患者的用药情况。结合产科教材、国内外指南等,对其路径用药给出推荐方案。结果500例产妇、7043条医嘱中,治疗药物使用比例最高的是产后出血预防用药、妇科洗液和促进子宫复旧的中成药;不合理用药比例为13.90%,排序居前3位的依次为无适应证用药、无特殊理由未按指南推荐用药和遴选药品不适宜;平均药占比为14.03%,其中中成药费用占药品费用的53.32%。结论自然临产经阴道分娩临床路径用药复杂,某些治疗药物使用的合理性缺少循证医学证据,临床路径用药方案尚需完善,以提高其治疗的经济性。Objective To provide a reference for optimizing the clinical pathway medlication recommendation for inpatients with sponta-ncous delivery and developing elinical pharmaceutical care.Methods A retrospective study was conducted to analyze the medication ofthe inpatients who chose the clinical pathway of spontaneous delivery in a hospital from January 2017 to Jume 2018.Based on the ob-stetric textbooks,domestic and foreign guidlelines,the clinical pathway medication regimen was recommended.Results Among the 500cases of parturient women and 7043 medical orlers,the top 3 dug types for the treatment were prophylactic medication for postpartumhemomrhage gynecological lotion and Chinese palent medicines for uterine involution.The proportion of irraional drug use was 13.90%,and the top 3 were drug use without indication,medication beyond the guidelines without special reasons and irational drug selec-tion.The average drug proportion was 14.03%o,and the cost of Chinese patent medicine acounted for 53.32%of the total drugcost.Conclusion The medication reginmen used for the treatment of inpatients wih spontaneous delivery clinical pathway is complicat-ed,and the rationality of some dnugs lacks evidence-hbased support.The clinical pathway medication regimens need to be optimized toimprove medication cost-effectiveness.
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