呼吸机治疗重症急性有机磷农药中毒呼吸衰竭的效果观察  

Observation on the effect of ventilator in treating severe acute organophosphorus pesticide poisoning respiratory failure

作　　者：何盈盈[1] 唐晨 李亚骐 He Yingying;Tang Chen;Li Yaqi(Department of Emergency Medicine,Guizhou Provincial People's Hospital,Guiyang,Guizhou,550005,China)

机构地区：[1]贵州省人民医院急诊内科,贵州贵阳550005

出　　处：《当代医学》2020年第36期126-128,共3页Contemporary Medicine

摘　　要：目的观察呼吸机治疗重症急性有机磷农药中毒呼吸衰竭患者临床效果。方法选取2018年8月至2019年8月本院收治的66例重症急性有机磷农药致呼吸衰竭患者,根据患者入院先后顺序分为实验组与参照组,各33例。实验组采用呼吸机治疗,参照组采用常规方法治疗,比较两组临床效果。结果实验组治疗总有效率高于参照组,差异有统计学意义(χ^2=5.3455,P<0.05)。实验组不良反应发生率低于参照组,差异有统计学意义(χ^2=4.6938,P<0.05)。两组患者自主呼吸恢复、意识恢复、插管、住院时间比较差异有统计学意义(t=9.9845、t=12.8717、t=10.0857、t=13.7657,P<0.05)。治疗后,两组动脉血氧分压(PaO2)、动脉血氧饱和度(SaO2)比较差异有统计学意义(t=29.8480、t=27.6071,P<0.05)。结论呼吸机治疗重症急性有机磷农药中毒致患者的临床疗效显著、安全,而且能促使患者尽快恢复自主呼吸、意识,缩短插管和住院时间,并有效改善患者血气分析指标。Objective To observe the clinical effect of ventilator in the treatment of severe acute organophosphorus pesticide poisoning patients with respiratory failure.Methods A total of 66 patients with severe acute organophosphorus pesticide poisoning respiratory failure were treated in our hospital from August 2018 to August 2019.According to the order of patients admitted to the hospital,all patients were divided into experimental group and reference group,with 33 cases in each group.The experimental group was treated with ventilator,and the reference group was treated with conventional methods.The clinical effects between the two groups were compared.Results The total effective rate of the experimental group was higher than that of the reference group,and the data between the groups were significantly different(χ^2=5.3455,P<0.05).The incidence of adverse reactions in the experimental group was lower than that in the reference group,and there was significant difference between the groups(χ^2=4.6938,P<0.05).There were statistically significant difference in the time of spontaneous breathing recovery,consciousness recovery,intubation,and hospitalization between the two groups(t=9.9845,t=12.8717,t=10.0857,t=13.7657,P<0.05).After treatment,the difference in arterial partial pressure of oxygen(PaO2)and arterial oxygen saturation(SaO2)between the two groups was statistically significant(t=29.8480,t=27.6071,P<0.05).Conclusion The clinical efficacy of ventilator in the treatment of severe acute organophosphorus pesticide poisoning patients with respiratory failure is significant and safe,and it can prompt patients to resume spontaneous breathing,consciousness,shorten the time of intubation and hospitalization,and effectively improve blood gas analysis indicators.

关 键 词：呼吸机 重症急性有机磷农药中毒 呼吸衰竭 临床效果 

分 类 号：R595.4[医药卫生—内科学] R563.8[医药卫生—临床医学]