近40年慢性萎缩性胃炎及胃癌前病变中医研究述评  

Review of Traditional Chinese Medicine Research on Chronic Atrophic Gastritis and Gastric Precancerous Lesions in the Past 40 Years

作　　者：王萍[1] 尹晓岚 张北华[1] 唐旭东[2] WANG Ping;YIN Xiaolan;ZHANG Beihua;TANG Xudong(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,100091;China Academy of Chinese Medical Sciences)

机构地区：[1]中国中医科学院西苑医院,北京市海淀区100091 [2]中国中医科学院

出　　处：《中医杂志》2020年第22期1943-1947,共5页Journal of Traditional Chinese Medicine

基　　金：国家重点研发计划项目(2017YFC1700601);国家中医药管理局国家中医临床研究基地业务建设科研专项(JDZX2015265)。

摘　　要：慢性萎缩性胃炎(CAG)及胃癌前病变(GPL)诊治在胃癌防治中占有重要地位。近40年来CAG及GPL的中医药研究在疾病诊断、风险监测、临床治疗、基础研究等方面取得了一定成果,但仍在目标定位、诊断规范性、研究科学性、疗效评价指标认可度等方面存在问题,严重影响研究的质量,制约中医药疗效和优势的体现。通过对上述问题的系统梳理,提出应以大数据为依托,制定病证结合的风险预测模型,从而制定适合我国国情的有效风险评估工具;建议统一CAG及GPL的诊断标准、细化病变分级分型标准,并及早采用中药进行有效干预。The diagnosis and treatment of chronic atrophic gastritis(CAG)and gastric precancerous lesions(GPL)play an important role in the prevention and treatment of gastric cancer.In the past 40 years,traditional Chinese medicine(TCM)research has achieved certain results in disease diagnosis,risk monitoring,clinical treatment,basic research,etc.,but there are still problems in target positioning,diagnostic standardization,scientific research,and recog nition of efficacy evaluation indicators,seriously affecting the quality of research and restricting the manifestation of the efficacy and TCM advantages.Through a systematic review of the above problems,it is proposed that big data should be used as the basis to develop a risk prediction model combining disease and syndrome,so as to develop an effective risk assessment tool suitable for China's national conditions;it is recommended to unify the diagnostic criteria of CAG and GPL,refine the classification of disease type standards,and to use Chinese medicine for effective intervention as early as possible.

关 键 词：慢性萎缩性胃炎 胃癌前病变 中医药研究 

分 类 号：R259[医药卫生—中西医结合]