子宫动脉频谱对妊娠期高血压疾病合并胎儿生长受限的诊断价值研究  

Study on the diagnostic value of uterine artery spectrum for hypertensive disorders of pregnancy complicated with fetal growth restriction

作　　者：李百玲[1] 侯丽颖 王婷[1] 张锐[1] LI Bai-Ling;HOU Li-Ying;WANG Ting(Department of Electrical Diagnosis,Changchun Obstetrics-Gynecology Hospital,Changchun,Jilin 130042,China)

机构地区：[1]长春市妇产医院电诊科,吉林长春130042

出　　处：《中国妇幼保健》2020年第23期4599-4602,共4页Maternal and Child Health Care of China

基　　金：吉林省卫生计生科技创新项目(20172C002)。

摘　　要：目的探讨子宫动脉频谱对妊娠期高血压疾病合并胎儿生长受限(FGR)的诊断价值。方法随机选取2018年1月-2019年12月在长春市妇产医院门诊进行产检并分娩的孕妇,分为正常组(A组,815例)、妊娠期高血压疾病组(B组,38例,单纯妊娠期高血压疾病,无并发症)、妊娠期高血压疾病合并FGR组(C组,34例)。于孕早期(孕11~14周)、孕中期(孕20~24周)测量双侧子宫动脉血流参数,比较子宫动脉舒张早期切迹发生率。结果在孕早期和孕中期,3组孕妇子宫动脉血流参数比较差异均有统计学意义(均P<0.05),C组孕妇子宫动脉血流参数均显著高于A组和B组(均P<0.05),A组和B组孕妇子宫动脉血流参数比较差异均无统计学意义(均P>0.05);3组孕妇子宫动脉舒张早期切迹发生率比较差异均有统计学意义(均P<0.05),A组孕妇子宫动脉舒张早期切迹发生率显著低于C组(均P<0.05)。结论孕早期和孕中期子宫动脉血流参数的变化可以预测妊娠期高血压疾病和FGR的发生。与孕早期比较,孕中期子宫动脉多普勒超声的预测价值更高。Objective To explore the diagnostic value of uterine artery spectrum for hypertensive disorders of pregnancy complicated with fetal growth restriction (FGR). Methods From January 2018 to December 2019,the pregnant women receiving prenatal examination and giving birth to their babies in Outpatient Department of Changchun Obstetrics-Gynecology Hospital were randomly selected and divided into normal group (A group,815 cases),hypertensive disorders of pregnancy group (B group,38 cases with simple hypertensive disorders of pregnancy,without complications),hypertensive disorders of pregnancy complicated with FGR group (C group,34 cases). Bilateral uterine artery blood flow parameters were measured during the first trimester of pregnancy (11-14 gestational weeks) and the second trimester of pregnancy (20-24 gestational weeks). The incidence rates of early diastolic notch of uterine artery were compared. Results During the first and the second trimesters of pregnancy,there were statistically significant differences in uterine artery blood flow parameters among the three groups (P<0. 05),uterine artery blood flow parameters in C group were statistically significantly higher than those in A group and B group (P<0. 05). There was no statistically significant difference in uterine artery blood flow parameters between A group and B group (P>0. 05);there were statistically significant differences in the incidence rates of early diastolic notch of uterine artery among the three groups (P<0. 05),the incidence rate of early diastolic notch of uterine artery in A group was statistically significantly lower than that in C group (P<0. 05). Conclusion The changes of uterine artery blood flow parameters during the first and the second trimesters of pregnancy can predict the onset of hypertensive disorders of pregnancy and FGR. Compared with the first trimester of pregnancy,the predictive value of uterine artery Doppler ultrasound during the second trimester of pregnancy is higher.

关 键 词：妊娠期高血压疾病 胎儿生长受限 子宫动脉频谱 

分 类 号：R714.24[医药卫生—妇产科学]