海南省新型冠状病毒肺炎输入与本土病例的临床特征比较  

Clinical characteristics comparative analysis of imported and local cases with COVID-19 in Hainan

作　　者：王姣[1] 林锋[1] 韩丽珍[1] 刘明 吴彪[1] 符娟[1] 韦超超 张艳茹 潘白玉 李晖[1] 吴涛[1] WANG Jiao;LIN Feng;HAN Lizhen;LIU Ming;WU Biao;FU Juan;WEI Chaocha;ZHANG Yanru;PAN Baiyu;LI Hui;WU Tao(Hainan People’s Hospital,Hainan Hospital Affiliated to Hainan Medical College,Haikou,Hainan 570311,China)

机构地区：[1]海南省人民医院,海南医学院附属海南医院,海南海口570311

出　　处：《中国热带医学》2020年第12期1163-1166,1171,共5页China Tropical Medicine

基　　金：海南省“南海名家”培养高层次人才项目。

摘　　要：目的观察、了解海南省69例新型冠状病毒肺炎患者的流行病学特征、临床特征、辅助检查和预后。方法收集海南省人民医院2020年1月22日至3月7日收治的69例新型冠状病毒肺炎患者的流行病学史、既往史、临床表现、实验室检查结果和影像学检查结果进行归纳与分析。根据病情分为普通/轻症组,危重/重症组,根据流行病学史分为输入病例与本地病例,回顾性分析其流行病学特征及临床资料,进一步对比两组间临床资料的差异。统计学处理采用Mann-Whitney U检验或χ~2检验。结果69例患者中,男性41例,女性28例,年龄28~83岁,30例既往有基础疾病史。主要临床表现为咳嗽(85.51%)、发热(81.16%)、乏力(46.38%),鼻塞、咽部不适少见。白细胞升高者9例,中性粒细胞百分比升高25例,淋巴细胞百分比降低33例,淋巴细胞绝对值减少42例,影像学检查肺部有炎症者66例。临床分型:轻型3例,普通型54例,重型3例,危重型9例,即非重症组(普通/轻型)57例,重症组(危重/重型)12例。69例患者,输入病例54例,78.26%,本地病例15例,两组临床表现与临床分型差异无统计学意义(P>0.05)。结论海南省CO-VID-19患者以普通型与轻型为主,输入性病例与本土病例临床特征相似。Objective To observe the epidemiology,clinical features,auxiliary examinations and prognosis of 69 cases with COVID-19 in Hainan province.Methods The epidemiological history,past history,clinical manifestations,laboratory 22 to March 7,2020 were collected.They were divided into non severe group and severe group according to patients’condition,and imported cases and indigenous cases according to the epidemiological history.And then we retrospectively analyzed their epidemiological and clinical data,further compared the differences between the two groups.Mann-Whitney U test and chisquare test were used in statistical analysis.ResultsAmong the 69 patients,41 were male,and 28 were female,aged 28-83 years,and 30 had a history of underlying disease.The main clinical manifestations were cough(85.51%),fever(81.16%),asthenia(46.38%).Nasal obstruction and pharyngeal discomfort were rare.9 cases had increased white blood cells,25 cases had increased neutrophil percentage,33 cases had decreased lymphocyte percentage,42 cases had decreased lymphocyte absolute value,and 66 cases had lung inflammation by imaging examination.Clinical classification:3 cases were mild,54 cases were normal,3 cases were severe,9 cases were critical,i.e.,57 cases were non-severe(normal/mild),12 cases were severe(critical/severe).Among 69 patients,54(78.26%)were imported cases and 15 were local cases.There was no significant difference between the two groups in clinical manifestations neither clinical typing(P>0.05).ConclusionThe main clinical types of COVID-19 patients are moderate type and mild type.There is no difference in clinical manifestations and clinical types between imported cases and indigenous cases.

关 键 词：新型冠状病毒肺炎 输入性 本土性 流行病学 临床特征 海南省 

分 类 号：R563.14[医药卫生—呼吸系统]