Complex relationships between physiological stress and endoparasite infections in natural populations  

作　　者：Claudia Romeo Lucas A.WAUTERS Francesca Santicchia Ben DANTZER Rupert Palme Adriano Martinoli Nicola Ferrari 

机构地区：[1]Department of Veterinary Medicine,Universita degli Stu di di Milano,Via Celoria 10,Milano,2133,Italy [2]bDepartment of Theoretical and Applied Sciences,Environment Analysis and Management Unit-Guido Tosi Research Group-Universita degli Studi delKInsubria,Via J.H.Dunant 3,Varese,21100,Italy [3]Department of Biology,Evolutionary Ecology Group,University of Antwerp,Universiteitsplein 1,Wilrijk,2610,Belgium [4]Department of Psychology,University of Michigan,530 Church Street,Ann Arbor,Ml,48109,USA [5]Department of Ecology and Evolutionary Biology,University of Michigan,830 North University,Ann Arbor,Ml,48109,USA [6]Unit of Physiology,Pathophysiology and Experimental En docri no logy,Department of Biomedical Scie nces,University of Veterinary Medicine Vienna,Veterinarplatz 1,Vienna,1210,Austria [7]Centro di Ricerca Coordinata Epidemiologia e Sorveglianza Molecolare delle Infezioni,Universita degli Studi di Milano,Milano,Italy

出　　处：《Current Zoology》2020年第5期449-457,共9页动物学报（英文版）

基　　金：Thanks to Zainab Almusawi and Teera Losch for helping in laboratory analysis,Candice Gagnaison,Laure Vanlauwe,and Mattia Panzeri for assistance with the fieldwork.We are grateful to the private land owners for access to their estates.Three anonymous reviewers provided constructive comments that helped us to improve the article.

摘　　要：Short-term elevation of glucocorticoids(GCs)is one of the major physiological mechanisms by which vertebrates cope with challenging environmental or social factors(stressors).However,when exposure to stressors occurs repeatedly or over a prolonged period of time,animals may experience chronic elevation of GCs,which reduces the immune response efficiency and can lead to higher intensity of parasitic infection.Here,we used invasive gray squirrels Sciurus carolinensis in troduced in Norther n Italy and their 2 most prevale nt gastrointesti nal parasites,the n ematode Strongyloides robustus and coccidia of the genus Eimeria,as a model to investigate relati on ships among macroparasite infection and concentrations of fecal glucocorticoid metabolites(FGMs),an integrated measure of circulating GCs.Our results revealed an association of FGMs with infection by St.robustus,but not with coccidia.Individuals with higher FGMs appear to be responsible for the greatest St.robustus egg shedding within gray squirrel populations,thus possibly acting as superspreaders.However,FGMs were negatively associated with adult St.robustus,suggesting that the abundance of adults of this nematode species does not induce elevation in FGMs,but is only affected by it through immun e-mediated effects on its fecun dity.Fin ally,the relati on ship betwee n St.robustus(both eggs and adult parasites)and FGMs was not linear,suggesting that only high levels of physiological stress in fluence parasite inf ection.Our fin dings highlight that the direction and magnitude of the stress-infection relationship may depend not only on the specific hostparasite system,but also on the different life stages of the same parasite.

关 键 词：fecal glucocorticoid metabolites invasive alien species parasites Sciurus carolinensis STRESS tree squirrel 

分 类 号：S852.7[农业科学—基础兽医学]