阿米卡星联合左氧氟沙星治疗急性重症细菌感染性腹泻的临床效果  

Clinical Effect of Amikacin Combined with Levofloxacin in the Treatment of Acute Severe Bacterial Infectious Diarrhea

作　　者：周墨 ZHOU Mo(Shenyang Fifth People's Hospital,Shenyang 110020,China)

机构地区：[1]沈阳市第五人民医院,辽宁沈阳110020

出　　处：《中国医药指南》2020年第32期89-90,共2页Guide of China Medicine

摘　　要：目的探究阿米卡星联合左氧氟沙星治疗急性重症细菌感染性腹泻的临床效果。方法将2018年1月至2018年12月我院收治的急性重症细菌感染性腹泻患者84例纳入研究,随机分为两组,每组42例。常规治疗基础上,对照组给予左氧氟沙星治疗,观察组给予阿米卡星联合左氧氟沙星治疗。对比两组治疗效果。结果观察组腹泻、腹痛、发热、呕吐等症状消退的时间短于对照组(P<0.05);观察组白细胞升高比率低于对照组,白细胞、脓细胞、红细胞转阴比率高于对照组(P<0.05);观察组治疗总有效率(97.62%)高于对照组(80.95%)(P<0.05)。结论阿米卡星联合左氧氟沙星在治疗急性重症细菌感染性腹泻患者中的疗效明显。Objective To explore the clinical eff ect of amikacin combined with levofl oxacin in the treatment of acute severe bacterial infectious diarrhea.Methods A total of 84 patients with acute severe bacterial infectious diarrhea from January 2018 to December 2018 were included in the study,randomly divided into two groups,42 cases in each group.On a routine basis,the control group was treated with levofl oxacin,the observation group was treated with amikacin combined with levofl oxacin.The therapeutic eff ect of the two groups was compared.Results The time for diarrhea,abdominal pain,fever,vomiting and other symptoms in the observation group to subside was shorter than that of the control group(P<0.05).The increase rate of white blood cells in the observation group was lower than that of the control group,and the conversion ratio of white blood cells,pus cells,and red blood cells was higher than that of the control group(P<0.05).The total eff ective rate of treatment in the observation group(97.62%)is higher than that of the control group(80.95%)(P<0.05).Conclusion Amikacin combined with levofl oxacin is eff ective in the treatment of acute severe bacterial infectious diarrhea.

关 键 词：急性重症细菌感染性腹泻 阿米卡星 左氧氟沙星 治疗 效果 

分 类 号：R442.2[医药卫生—诊断学]