视网膜光凝治疗糖尿病性视网膜病变的临床疗效  

Clinical Effect of Retinal Photocoagulation in the Treatment of Diabetic Retinopathy

作　　者：吕涛 侯传俊 LV Tao;HOU Chuanjun(The First Hospital of Dandong City,Dandong 118000,China)

机构地区：[1]丹东市第一医院,辽宁丹东118000

出　　处：《中国医药指南》2020年第32期105-106,共2页Guide of China Medicine

摘　　要：目的探讨视网膜光凝治疗糖尿病性视网膜病变的临床疗效。方法选择2017年7月至2018年7月95例DR分期Ⅲ~Ⅳ期的糖尿病性视网膜病变患者作为研究对象,给予这些患者视网膜光凝治疗。比较两组患者治疗后2、4、8、12、24周的视力增加值以及治疗前、治疗后1 d、4周、8周、24周的视野平均阈值敏感度。结果Ⅲ期组患者治疗后2周、4周、8周、12周、24周的视力增加值分别为(0.105±0.017)、(0.152±0.052)、(0.485±0.057)、(0.637±0.019)、(0.709±0.044),Ⅳ期组患者分别为(0.066±0.021)、(0.084±0.014)、(0.177±0.042)、(0.372±0.038)、(0.512±0.037)。两组患者治疗后的视力均在不断增加,且Ⅲ期组患者的视力增加值明显高于Ⅳ期组,比较具有统计学意义(P<0.05)。两组患者治疗后1 d视野平均阈值敏感度均较治疗前明显降低,比较具有统计学意义(P<0.05),之后又逐步恢复,基本在治疗后24周恢复到治疗前水平,两组患者治疗前、治疗后1 d、4周、8周、24周的视野平均阈值敏感度比较均无统计学意义(P>0.05)。结论视网膜光凝治疗糖尿病性视网膜病变能有效改善视力,且越早治疗越好,但视网膜光凝有一定的激光损伤性,不过这种激光损伤是可逆的。Objective To explore the clinical efficacy of retinal photocoagulation in the treatment of diabetic retinopathy.Methods From July 2017 to July 2018,95 patients with diabetic retinopathy with DR stagesⅢtoⅣwere selected as the research objects,and these patients were given retinal photocoagulation therapy.The visual acuity increase at 2,4,8,12,and 24 weeks after treatment and the average threshold sensitivity of visual fi eld before treatment,1 d,4 weeks,8 weeks,and 24 weeks after treatment were compared between the two groups.Results The visual acuity gains of patients in stageⅢgroup at 2 weeks,4 weeks,8 weeks,12 weeks and 24 weeks after treatment were(0.105±0.017),(0.152±0.052),(0.485±0.057),(0.637±0.019),(0.709±0.044),the patients in stageⅣgroup were(0.066±0.021),(0.084±0.014),(0.177±0.042),(0.372±0.038),(0.512±0.037).The visual acuity of the two groups of patients was continuously increasing after treatment,and the visual acuity increase of the patients in the stageⅢgroup was signifi cantly higher than that in the stageⅣgroup,which was statistically signifi cant(P<0.05).The average threshold sensitivity of the visual fi eld of the two groups of patients 1 day after treatment was signifi cantly lower than that before treatment,which was statistically signifi cant(P<0.05),and then gradually recovered,basically returning to the pre-treatment level 24 weeks after treatment.There was no statistically signifi cant comparison of the average threshold sensitivity of the visual fi eld before treatment,1 day,4 weeks,8 weeks,and 24 weeks after treatment(P>0.05).Conclusion Retinal photocoagulation can eff ectively improve vision in the treatment of diabetic retinopathy,and the sooner the treatment,the better,but retinal photocoagulation has certain laser damage,but this laser damage is reversible.

关 键 词：糖尿病性视网膜病变 视网膜光凝 视力 视野平均阈值敏感度 

分 类 号：R587.2[医药卫生—内分泌] R774.1[医药卫生—内科学]