不同剂量连续性肾脏替代治疗应用于重症肺炎合并脓毒症的效果分析  

Analysis on the Effect of Continuous Renal Replacement Therapy with Different Doses Applied in Severe Pneumonia Complicated with Sepsis

作　　者：杨勇[1] YANG Yong(Department of Critical Care Medicine,Changsha Central Hospital,Changsha 410004,China)

机构地区：[1]长沙市中心医院重症医学科,湖南长沙410004

出　　处：《临床医学工程》2020年第12期1651-1652,共2页Clinical Medicine & Engineering

摘　　要：目的探讨不同剂量连续性肾脏替代治疗应用于重症肺炎合并脓毒症的效果。方法选择2018年1月至2019年12月我院收治的重症肺炎合并脓毒症患者100例,随机分为两组各50例。对照组接受低剂量连续性肾脏替代治疗,研究组接受高剂量连续性肾脏替代治疗,比较两组的治疗效果。结果治疗前,两组的炎性因子水平、SOFA评分、APACHEⅡ评分无显著差异(P>0.05);治疗后,研究组的hs-CRP、TNF-α、SAA水平以及SOFA评分、APACHEⅡ评分低于对照组(P<0.05)。结论高剂量连续性肾脏替代治疗对于重症肺炎合并脓毒症的效果优于低剂量,可有效改善患者的炎性反应,缓解病情。Objective To explore the effect of continuous renal replacement therapy with different doses applied in severe pneumonia complicated with sepsis.Methods 100 patients with severe pneumonia complicated with sepsis admitted to our hospital from January 2018 to December 2019 were selected and randomly divided into two groups,with 50 patients in each group.The control group received low-dose continuous renal replacement therapy,and the study group received high-dose continuous renal replacement therapy.The therapeutic effects of two groups were compared.Results Before treatment,no statistical difference was found between two groups in the levels of inflammatory factors,SOFA score and APACHEⅡ score(P>0.05);After treatment,the levels of hs-CRP,TNF-α and SAA,SOFA score and APACHEⅡ score of study group were lower than those of control group(P<0.05).Conclusions High-dose continuous renal replacement therapy for severe pneumonia complicated with sepsis has better effect than low-dose continuous renal replacement therapy,which can effectively improve patients'inflammatory response and alleviate the disease condition.

关 键 词：不同剂量 连续性肾脏替代治疗 重症肺炎合并脓毒症 治疗效果 

分 类 号：R563[医药卫生—呼吸系统]