水貂阿留申病毒研究进展  

Research progress of Aleutian virus in mink

作　　者：葛桂阳 李东丽 徐宁 栾美慧 郜艳雪 刘艺 宫庆龙[1] 麻宝艺 盛陈艳 孙志博 冷雪[2] 杜锐[3] GE Gui-yang;LI Dong-li;XU Ning;LUAN Mei-hui;GAO Yan-xue;LIU Yi;GONG Qing-long;MA Bao-yi;SHENG Chen-yan;SUN Zhi-bo;LENG Xue;DU Rui(College of Animal Science and Technology J ilin Agricultural University,Changchun 130118,China;College of Chinese Medicine Materials,Jilin Agricultural University,Changchun 130118,China;Key Laboratory of Animal Production,Product Quality and Security,Ministry of Education of China/Laboratory of Production and Product Application of Sika Deer of Jilin Province,Changchun 130118,China)

机构地区：[1]吉林农业大学动物科学技术学院,吉林长春130118 [2]吉林农业大学中药材学院,吉林长春130118 [3]教育部动物生产及产品质量安全重点实验室,吉林省梅花鹿生产与产品应用研究室,吉林长春130118

出　　处：《中国兽医学报》2020年第11期2276-2280,共5页Chinese Journal of Veterinary Science

基　　金：国家重点研发计划资助项目(2018YFC1706600);吉林省科技发展计划资助项目(20190304004YY,20190301004NY)。

摘　　要：水貂阿留申病(Aleutian mink disease,AMD)是由水貂阿留申病毒(Aleutian mink disease virus,AMDV)引起的一种慢性、进行性传染病,是危害世界养貂业的重要疫病之一。由于AMDV具有抗体依赖性增强作用和特殊的致病机制,目前尚未开发出有效的疫苗。本文从AMDV的起源、遗传进化、宿主范围、传播途径和病毒的复制机制等几方面对AMDV的研究现状进行探讨,为今后AMD的致病机制及防控的研究提供参考。Aleutian mink disease(AMD)is a chronic and progressive infectious disease caused by AMDV.It is one of the most important diseases that harm the mink industry in the world.Due to antibody-dependent potentiation and specific pathogenic mechanisms of AMDV,effective vaccines have not yet been developed.In this paper,the origin,genetic evolution,host range,route of transmission and replication mechanism of mink Aleutian virus are discussed,which will provide reference for the research of pathogenicity mechanism and prevention and control of mink Aleutian virus in the future.

关 键 词：细小病毒 水貂阿留申病毒 遗传进化 

分 类 号：S855.3[农业科学—临床兽医学]