慢性阻塞性肺疾病影像诊断研究进展  

Research progress in imaging diagnosis of chronic obstructive pulmonary disease

作　　者：朱丹 刘靖 席芊(审校)[1] ZHU Dan;LIU Jing;XI Qian(Department of Radiology,Shanghai East Hospital,Tongji University School of Medicine,Shanghai 200120,China)

机构地区：[1]同济大学附属东方医院医学影像科,上海200120

出　　处：《国际医学放射学杂志》2020年第6期676-680,共5页International Journal of Medical Radiology

基　　金：国家自然科学基金(81301200);上海市科学技术委员会科研项目(19411951400);上海市卫生和计划生育委员会科研项目(201740207)。

摘　　要：慢性阻塞性肺疾病(COPD)是一种广泛的弥漫性肺部疾病,通过分析其放射学特征表现能够为该病的定量、定性、分型以及预后评估等提供更精准的临床决策。近年CT定量分析等方法为评估肺气肿改变及小气道病变提供了一种无创性手段,更加深入地诠释了COPD复杂的异质性表型及病理生理机制。就定量CT、4D动态CT测量、CT通气灌注显像等成像方法在COPD中的应用进展予以综述。Chronic obstruction lung disease(COPD)is a widespread diffuse lung disease.Analyzing its radiological characteristics can provide more accurate clinical decisions for the quantitative,qualitative,typing and prognosis assessment of COPD.In recent years,CT quantitative analysis and other methods have enabled a non-invasive evaluation of emphysema changes and small airway disease,and further explained the complex heterogeneous phenotypes and pathophysiological mechanisms of COPD.In this article,the application progress of imaging methods such as quantitative CT,4D dynamicventilation CT,and Ventilation-perfusion imaging in COPD are reviewed.

关 键 词：慢性阻塞性肺疾病 定量CT 动态通气CT 通气灌注显像 血管分析 

分 类 号：R563[医药卫生—呼吸系统] R445[医药卫生—内科学]