西吡氯铵泡沫含漱在老年原发性干燥综合征患者口腔环境管理中的应用  

Effect of Gargle with CetylpyridiniumChloride on Oral Environmental Management in Elderly Patients with Primary Sjogren's Syndrome

作　　者：艾香艳[1] 刘庆芬[2] 顾纪芳 赵福涛[1] Ai Xiangyan;Liu Qingfen;Gu Jifang;Zhao Futao(Department of Rheumatology and Immunology,Ninth People's Hospital Affiliated toMedical College of Shanghai Jiaotong University,Shanghai,201999,P.R.China;Nursing Clinic,Ninth People's Hospital Affiliated to Medical College of Shanghai Jiaotong University,Shanghai,201999,P.R.China)

机构地区：[1]上海交通大学医学院附属第九人民医院风湿免疫科,上海201999 [2]上海交通大学医学院附属第九人民医院护理门诊,上海201999

出　　处：《老年医学与保健》2020年第6期1073-1076,共4页Geriatrics & Health Care

基　　金：上海交通大学医学院附属第九人民医院临床研究型MDT项目(201910)。

摘　　要：目的探讨西吡氯铵泡沫含漱方法在老年原发性干燥综合征(pimary Sjogren's sydrome,pSS)患者口腔环境管理中的应用效果。方法选择2019年1月-2020年9月在上海交通大学医学院附属第九人民医院风湿免疫科治疗的老年pSS患者80例,采用随机数字表法分为观察组和对照组,每组40例。对照组采用通常的口腔清洁方法,观察组在对照组的基础上,加用西砒氯铵泡沫含漱方法进行口腔护理,3次/d。观察比较2组在口腔管理前后口干程度评分、唾液pH值、唾液流速及并发症(口腔溃疡、牙龈炎及口臭)发生的情况。结果口腔护理管理4周时,观察组失访6例,对照组失访4例,观察组和对照组随访总有效率分别为85.00%(34/40)和90.00%(36/40),差异无统计学意义(p>0.05);观察组的主观口干评分明显低于对照组(p<0.05),唾液pH值和唾液流率均明显高于对照组(p<0.05),口腔溃疡、牙龈炎及口臭发生率均明显低于对照组,差异均有统计学意义(p<0.05)。结论西吡氯铵泡沫含漱方法能有效缓解老年pSS患者口干症状和改善口腔局部环境,有利于老年pSS口腔环境的健康管理。Objective To explore the application effect of gargle with cetylpyridinium chloride on oral environmental management in elderly patients with primary Sjogren's syndrome(pSS).Methods 80 elderly patients with pSS who were treated in the Department of Rheumatology and Immunology of Ninth People's Hospital Affiliated to Medical College of Shanghai Jiaotong University from January 2019 to September 2020 were selected and divided randomly into observation group and control group,40 cases in each group.The control group adopts the routine oral cleaning method,and the observation group received gargle with cetylpyridiniumchloride foam,three times a day.The scores of dry mouth,saliva pH,saliva flow rate and complications(oral ulcers,gingivitis and halitosis)before and after oral management were evaluated and compared between the two groups.Results After 4 weeks of oral care management,6 cases were lost in the observation group and 4 cases were lost in the control group.The total effective rate of follow-up in the observation group and control group was 85.00%(34/40)and 90.00%(36/40),respectively,there was no difference statistical significance(P>0.05).The subjective dry mouth score of the observation group was significantly lower than that of the control group(P<0.05),the salivary pH value and saliva flow rate were significantly higher than those of the control group(P<0.05),and the incidence of oral ulcer,gingivitis and halitosis in the observation group was significantly lower than that in the control group,the differences were statistically significant(P<0.05).Conclusion Gargle with cetylpyridiniumchloride foamcan effectively relieve the symptoms of dry mouth in elderly patients with pSS and improve the local oral environment,which is beneficial to the health management of the oral environment of elderly pSS patients.

关 键 词：老年 原发性干燥综合征 口腔环境 西吡氯铵泡沫剂 护理 

分 类 号：R473.5[医药卫生—护理学]