药物洗脱球囊在脑动脉疾病治疗中的研究进展  

Research progress of drug-eluting balloon in the treatment of cerebral artery diseases

作　　者：李宪东 霍龙文 宋康佳 张文彬[1] 严进华 王守春[1] Li Xiandong;Huo Longwen;Song Kangjia;Zhang Wenbin;Yan Jinhua;Wang Shouchun(Department of Neurology,the First Hospital of Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学第一医院神经内科,长春130021

出　　处：《中国脑血管病杂志》2020年第12期766-771,共6页Chinese Journal of Cerebrovascular Diseases

基　　金：吉林省科技创新中心建设项目(20190902002TC)。

摘　　要：球囊血管成形术和支架置入术是血管内介入治疗的主要方法。然而,对于内膜增生等原因导致的血管内或支架内再狭窄,其疗效仍不理想。药物洗脱球囊(DEB)在冠状动脉的应用已展现了良好的效果。由于存在相同的动脉粥样硬化病理基础及再狭窄机制,对于脑动脉病变DEB可能同样有效。该文综述了DEB的基本知识及在冠状动脉和脑动脉疾病中的应用,旨在提高对DEB的认识。Balloon angioplasty and stenting are the main endovascular treatment modalities.However,the rate of restenosis is high due to neo-intimal hyperplasia.The application of the drug-eluting balloon(DEB)in coronary arteries has achieved good outcomes.Because of the same pathological feature of atherosclerosis and restenosis mechanism,DEB may be equally effective for cerebral artery diseases.This review summarizes the basic knowledge of DEB and its application in coronary and cerebral artery diseases,aiming to improve the understanding of DEB.

关 键 词：药物洗脱球囊 支架 球囊扩张术 再狭窄 综述 

分 类 号：R543.5[医药卫生—心血管疾病]