单中心维持性血液透析患者生存现状的横断面研究  

A cross-sectional study on the survival status of single-center maintenance hemodialysis patients

作　　者：王国伟 刘思逸 周静[1] 罗来敏[1] WANG Guowei;LIU Siyi;ZHOU Jing;LUO Laimin(Department of Nephrology,The First Affiliated Hospital of Nanchang University,Nanchang 330006,Jiangxi,China)

机构地区：[1]南昌大学第一附属医院肾内科,江西南昌330006

出　　处：《上海医学》2020年第12期740-744,共5页Shanghai Medical Journal

基　　金：江西省卫生和计划生育委员会科技计划(20175076)。

摘　　要：目的通过调查维持性血液透析(maintenance hemodialysis,MHD)患者的生存现状,分析影响其生活质量的因素,为改善其生活质量提供科学依据。方法采用横断面调查的方法,使用肾脏疾病生活质量简表(KDQOL-SF TM 1.3)评估在南昌大学第一附属医院血液净化中心行MHD患者的生活质量,收集其人口学信息和临床资料,采用多重线性回归分析其独立影响因素。结果共296例MHD患者纳入统计学分析,一般健康相关生活质量简表(SF-36)总分为(51.45±17.62)分,肾脏病相关生活质量(KDTA)总分为(57.07±10.40)分。年龄[偏回归系数(β’)=-0.267,P<0.01]、透析血流量(β’=0.117,P<0.01)、血清白蛋白水平(β’=0.482,P<0.05)为影响SF-36总分的独立危险因素;年龄(β’=-0.230,P<0.01)、原发病为糖尿病(β’=-3.792,P<0.01)、透析血流量(β’=0.055,P<0.05)为影响KDTA总分的独立危险因素。结论影响MHD患者生活质量的因素较多,应针对相关因素加强CKD患者的管理,改善其生活质量。Objective To analyze the factors affecting the quality of life of patients with maintenance hemodialysis(MHD)by investigating the survival status,and to provide a scientific basis for improving the quality of life of MHD patients.Methods The kidney disease quality of life short form 1.3(KDQOL-SF TM 1.3)was used for quality of life assessment using a cross-sectional survey.Demographic and clinical data of MHD patients were collected.Multiple linear regression analysis was used to analyze independent risk factors affecting the quality of life of MHD patients.Results The total score of health-related quality of life(SF-36)was 51.45±17.62,and the total score of kidney disease targets areas(KDTA)was 57.07±10.40.Age(partial regrexion coefficient[β’]=-0.267,P<0.01),dialysis blood flow(β’=0.117,P<0.01),and serum albumin level(β’=0.482,P<0.05)were the independent risk factors of the total score of SF-36.Age(β’=-0.230,P<0.01),diabetes mellitus(β’=-3.792,P<0.01),and dialysis blood flow(β’=0.055,P<0.05)were the independent risk factors of the total score of KDTA.Conclusion There are many factors affecting the quality of life of patients with MHD.It is essential to strengthen management of chronic kidney disease in response to these factors,so as to improve the quality of life of patients.

关 键 词：横断面研究 维持性血液透析 生活质量 KDQOL-SF TM 1.3量表 

分 类 号：R692.5[医药卫生—泌尿科学]