COVID-19 or non-COVID viral pneumonia:How to differentiate based on the radiologic findings?  

作　　者：Azadeh Eslambolchi Ana Maliglig Amit Gupta Ali Gholamrezanezhad 

机构地区：[1]Independent Radiologist Researcher,Bellevue,WA 98005,United States [2]Department of Radiology,Cardiothoracic and Advanced Body Imaging Division,Integrated Credential Committee,Clinical Radiology and Medicine,Keck School of Medicine,University of Southern California(USC)of Southern California(USC),Los Angeles,CA 90033,United States [3]Department of Radiology,Case Western Reserve University,Cardiothoracic Division,Modality Director Diagnostic Radiography,University Hospital Cleveland Medical Center,Cleveland,OH 44106,United States [4]Department of Radiology,Keck School of Medicine,University of Sothern California(USC),Los Angeles,CA 90033,United States

出　　处：《World Journal of Radiology》2020年第12期289-301,共13页世界放射学杂志（英文版）（电子版）

摘　　要：Influenza viruses were responsible for most adult viral pneumonia.Presently,coronavirus disease 2019(COVID-19)has evolved into serious global pandemic.COVID-19 outbreak is expected to persist in months to come that will be synchronous with the influenza season.The management,prognosis,and protection for these two viral pneumonias differ considerably and differentiating between them has a high impact on the patient outcome.Reverse transcriptase polymerase chain reaction is highly specific but has suboptimal sensitivity.Chest computed tomography(CT)has a high sensitivity for detection of pulmonary disease manifestations and can play a key-role in diagnosing COVID-19.We reviewed 47 studies and delineated CT findings of COVID-19 and influenza pneumonia.The differences observed in the chest CT scan can be helpful in differentiation.For instance,ground glass opacities(GGOs),as the most frequent imaging finding in both diseases,can differ in the pattern of distribution.Peripheral and posterior distribution,multilobular distribution,pure or clear margin GGOs were more commonly reported in COVID-19,whereas central or peri-bronchovascular GGOs and pure consolidations were more seen in influenza A(H1N1).In review of other imaging findings,further differences were noticed.Subpleural curvilinear lines,sugar melted sign,intra-lesional vascular enlargement,reverse halo sign,and fibrotic bands were more reported in COVID-19 than H1N1,while air space nodule,tree-in-bud,bronchiectasia,pleural effusion,and cavitation were more seen in H1N1.This delineation,when combined with clinical manifestations and laboratory results may help to differentiate these two viral infections.

关 键 词：CORONAVIRUS COVID-19 Computed tomography Viral pneumonia H1N1 INFLUENZA 

分 类 号：R563.1[医药卫生—呼吸系统]