通脉活血益气方预防老年股骨粗隆间骨折术后深静脉血栓形成临床研究  

Clinical Study on Tongmai Huoxue Yiqi Prescription in Preventing Deep Venous Thrombosis After Surgery of Senile Intertrochanteric Fracture

作　　者：何龙[1] 葛占洲[1] 周瑾[1] HE Long;GE Zhanzhou;ZHOU Jin

机构地区：[1]濮阳市中医院骨五科,河南濮阳457000

出　　处：《新中医》2020年第22期77-79,共3页New Chinese Medicine

摘　　要：目的:观察通脉活血益气方在预防老年股骨粗隆间骨折术后深静脉血栓形成中的作用。方法:选取老年股骨粗隆间骨折手术患者120例,按随机数字表法分为对照组和观察组各60例。对照组给予常规西医治疗及功能锻炼预防深静脉血栓形成,观察组在对照组基础上联合通脉活血益气方进行防治,均治疗15天。比较2组术前、术后第1天及第15天血液流变学、D-二聚体变化;每天检查双下肢血管彩超,观察深静脉血栓是否形成;记录治疗期间不良反应情况。结果:术后第1天,2组D-二聚体水平较术前升高(P<0.05);术后第15天,2组D-二聚体水平较术后第1天降低(P<0.05),且观察组D-二聚体水平低于对照组(P<0.05)。治疗前,2组全血黏度、血浆黏度、纤维蛋白原指标比较无统计学意义(P>0.05)。治疗后,2组全血黏度、血浆黏度、纤维蛋白原水平较治疗前降低,且观察组各项指标均低于对照组,差异均有统计学意义(P<0.05)。术后第15天,观察组深静脉血栓发生率为1.67%(1/60),低于对照组11.67%(7/60),差异有统计学意义(P<0.05)。结论:通脉活血益气方可以有效预防老年股骨粗隆间骨折术后深静脉血栓的形成,无不良反应,可进一步推广应用。Objective:To observe the effect of Tongmai Huoxue Yiqi prescription in preventing deep venous thrombosis after surgery of senile intertrochanteric fracture. Methods: A total of 120 cases of senile patients undergoing surgery of intertrochanteric fracture were divided into the control group and the observation group according to the random number table method,60 cases in each group. The control group was given routine western medicine treatment and functional exercise for preventing deep venous thrombosis,and the observation group was additionally given Tongmai Huoxue Yiqi prescription for prevention and treatment based on the treatment of the control group. Both groups were treated for fifteen days. Before surgery as well as on the 1 stand 15 thdays after surgery,the changes in hemorheology and D-dimer were compared between the two groups. Blood vessels of both lower extremities were examined by color Doppler ultrasound every day,and deep venous thrombosis was observed. The occurrence of adverse reactions during treatment was recorded. Results:On the 1 st day after surgery, the D-dimer levels in the two groups were increased when compared with those before treatment(P<0.05);on the 15 thday after surgery,the levels in the two groups were decreased when compared with those on the 1 st day after treatment(P<0.05);the level in the observation group was lower than that in the control group(P<0.05). Before treatment, when compared indexes including whole blood viscosity, plasma viscosity and fibrinogen between the two groups,there was no significance in the difference(P>0.05). After treatment,the levels of whole blood viscosity,plasma viscosity and fibrinogen in the two groups were decreased when compared with those before treatment,and each index in the observation group was lower than that in the control group,differences being significant(P<0.05). On the 15 thday after surgery,the deep venous thrombosis incidence was 1.67%(1/60) in the observation group,lower than that of 11.67%(7/60)in the control group,the differe

关 键 词：股骨粗隆间骨折术后 深静脉血栓 通脉活血益气方 D-二聚体 血液流变学 不良反应 

分 类 号：R683[医药卫生—骨科学]