成纤维细胞生长因子21在糖尿病视网膜病变中的研究进展  

Research progress of fibroblast growth factor 21 in diabetic retinopathy

作　　者：刘畅 谭薇 Chang Liu;Wei Tan(Department of Ophthalmology, the Third Affiliated Hospital of Zunyi Medical University, Zunyi City Eye Clinic Medical Center, Zunyi 563000, Guizhou Province, China)

机构地区：[1]遵义医科大学第三附属医院眼科遵义市眼科临床医学中心,中国贵州省遵义市563000

出　　处：《国际眼科杂志》2021年第1期71-74,共4页International Eye Science

基　　金：国家自然科学基金项目(No.81660162)。

摘　　要：成纤维细胞生长因子21(FGF21)作为新近发现的内源性调节因子,是研究的热点,其在糖尿病视网膜病变中起着重要的作用,因此近年来FGF21逐渐受到人们关注。本文对FGF21的分子结构、生物学功能及其与炎症反应的关系、在糖尿病视网膜病变病理进程中的作用等方面内容进行探讨。As a newly discovered endogenous regulator,fibroblast growth factor 21(FGF21)becomes hot topic in recent professional research.It plays an important role in diabetic retinopathy recently.Moreover,FGF21 has attracted more and more attention in recent years.This paper discussed the molecular structure of FGF 21,biological function,relationship between FGF21 and inflammatory response and role in the pathological process of diabetic retinopathy.

关 键 词：成纤维细胞生长因子21 眼部新生血管 糖尿病视网膜病变 脂联素 

分 类 号：R58[医药卫生—内分泌]